P19906
1-苯基双胍 盐酸盐
98%
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线性分子式:
C6H5NHC(=NH)NHC(=NH)NH2·HCl
化学文摘社编号:
分子量:
213.67
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-239-2
MDL number:
Assay:
98%
Form:
powder
InChI key
FHUDRDSKZQDCBC-UHFFFAOYSA-N
InChI
1S/C8H11N5.ClH/c9-7(10)13-8(11)12-6-4-2-1-3-5-6;/h1-5H,(H6,9,10,11,12,13);1H
SMILES string
Cl.NC(=N)NC(=N)Nc1ccccc1
assay
98%
form
powder
mp
244-247 °C (lit.)
Stephanie C Tjen-A-Looi et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 302(7), R833-R844 (2011-12-30)
Stimulation of cardiopulmonary receptors with phenylbiguanide (PBG) elicits depressor cardiovascular reflex responses, including decreases in blood pressure and heart rate mediated in part by the brain stem parasympathetic cardiac neurons in the nucleus ambiguus (NAmb). The present study examined NAmb
Kei Takano et al.
International journal of molecular sciences, 21(4) (2020-02-26)
Melanin in the epidermis is known to ultimately regulate human skin pigmentation. Recently, we exploited a phenotypic-based screening system composed of ex vivo human skin cultures to search for effective materials to regulate skin pigmentation. Since a previous study reported
Daniela M Sartor et al.
Naunyn-Schmiedeberg's archives of pharmacology, 376(4), 241-252 (2007-11-17)
Cholecystokinin (CCK) elicits a sympathetic vasomotor reflex that is implicated in gastrointestinal circulatory control. We sought to determine (1) the site in the solitary tract nucleus (NTS) responsible for mediating this reflex and (2) the possible involvement of excitatory amino
Angiotensin-(1-7) and baroreflex function in nucleus tractus solitarii of (mRen2)27 transgenic rats.
Debra I Diz et al.
Journal of cardiovascular pharmacology, 51(6), 542-548 (2008-05-14)
Endogenous angiotensin (Ang)-(1-7) enhances, while Ang II attenuates, baroreceptor sensitivity (BRS) for reflex control of heart rate (HR) in Sprague-Dawley (SD) rats. In (mRen2)27 renin transgenic rats [(mRen2)], there is overexpression of the mouse Ren2 gene in brain, leading to
Colleen J Thomas et al.
Clinical and experimental pharmacology & physiology, 38(7), 410-415 (2011-04-15)
1. Cardiac natriuretic peptides act on cardiopulmonary chemoreceptor afferents to enhance the von Bezold-Jarisch reflex (BJR). Activity of the natriuretic peptide particulate guanylyl cyclase receptor is essential for full expression of the BJR. Whether natriuretic peptides act directly on cardiac
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