产品名称
双(对硝基苯基)磷酸盐 钠盐, ≥99% (TLC)
InChI key
NXXNKMXTNUUECE-UHFFFAOYSA-N
InChI
1S/C12H9N2O8P.Na.H/c15-13(16)9-1-5-11(6-2-9)21-23(19,20)22-12-7-3-10(4-8-12)14(17)18;;/h1-8H,(H,19,20);;
SMILES string
[Na].OP(=O)(Oc1ccc(cc1)N(=O)=O)Oc2ccc(cc2)N(=O)=O
assay
≥99% (TLC)
form
powder
impurities
≤0.05% free p-nitrophenol
solubility
water: 20 mg/mL, clear to very slightly hazy
storage temp.
−20°C
Quality Level
General description
磷酸二酯酶底物
Application
双( p -硝基苯基)磷酸钠盐已被用作磷酸二酯酶 (PDE) 活性估计的底物。 在 PDE 抑制试验中也用作底物。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Sales PB, et al.
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6-Nitrobenzimidazole derivatives: Potential phosphodiesterase inhibitors: Synthesis and structure-activity relationship
Khan KM, et al.
Bioorganic & Medicinal Chemistry, 20(4), 1521-1526 (2012)
Elution of tightly bound solutes from concanavalin A Sepharose: Factors affecting the desorption of cottonmouth venom glycoproteins
Soper AS and Aird SD
Journal of Chromatography A, 1154(1-2), 308-318 (2007)
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Drug metabolism and disposition: the biological fate of chemicals, 38(2), 323-331 (2009-11-20)
Both mRNA and protein levels of the carboxylesterase (CES) isozymes, hCE1 and hCE2, in Caco-2 cells increase in a time-dependent manner, but hCE1 levels are always higher than those of hCE2. In human small intestine, however, the picture is reversed
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FimX is a large multidomain protein containing an EAL domain and involved in twitching motility in Pseudomonas aeruginosa. We present here two crystallographic structures of the EAL domain of FimX (residues 438-686): one of the apo form and the other
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