SMB00706
番茄红素
≥98% (HPLC), from tomato
别名:
ψ,ψ-胡萝卜素, 2,6,10,14,19,23,27,31-八甲基-三十二烷-2,6,8,10,12,14,16,18,20,22,24,26,30-十三烯
生物来源
tomato
质量水平
方案
≥98% (HPLC)
表单
powder
分子量
536.87
储存条件
protect from light
溶解性
THF: 1 mg/mL
chloroform: 5 mg/mL
应用
metabolomics
vitamins, nutraceuticals, and natural products
运输
dry ice
储存温度
−20°C
SMILES字符串
C\C(C)=C\CC\C(C)=C\C=C\C(C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(C)\C=C\C=C(/C)CC\C=C(\C)C
InChI
1S/C40H56/c1-33(2)19-13-23-37(7)27-17-31-39(9)29-15-25-35(5)21-11-12-22-36(6)26-16-30-40(10)32-18-28-38(8)24-14-20-34(3)4/h11-12,15-22,25-32H,13-14,23-24H2,1-10H3/b12-11+,25-15+,26-16+,31-17+,32-18+,35-21+,36-22+,37-27+,38-28+,39-29+,40-30+
InChI key
OAIJSZIZWZSQBC-GYZMGTAESA-N
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一般描述
番茄红素是一种无环类胡萝卜素色素，是一种具有生物活性的天然化合物，通常由西瓜、粉红番石榴、番茄等红色水果和蔬菜以及光合藻类产生。目前研究表明，这种植物代谢物是一种抑制剂，可能具有多种生物活性，包括抗氧化、抑制癌症、辐射防护、抗癌和抗炎特性。
应用
番茄红素已用于：
- 分析其对体外小鼠表皮细胞系皮肤肿瘤的化学预防作用
- 作为高效液相色谱(HPLC)定量的参考标准品，分析哺乳动物细胞系中内源性类胡萝卜素的抗氧化能力
- 作为高效液相色谱(HPLC)的参考标准品，鉴定酿酒酵母工程菌中的类胡萝卜素
番茄红素是从植物中提取的天然产物，可用于化合物筛选库、代谢组学、植物化学和药物开发研究。
生化/生理作用
已发现番茄红素具有抗口腔癌活性，并且可以通过下调NOX4而抑制人肝腺癌细胞的转移。番茄红素还被发现是心血管疾病患者的有益补充剂。
西红柿中的抗氧化剂微量营养素，与降低癌症和心血管疾病风险有关。通过间隙连接蛋白 43 的表达上调促进细胞间间隙连接通讯以及抑制培养中癌细胞增殖。抑制胆固醇合成以及促进低密度脂蛋白降解。
特点和优势
- 适用于多种研究应用的优质化合物
- 兼容HPLC 和质谱技术
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Alireza Milani et al.
British journal of pharmacology, 174(11), 1290-1324 (2016-10-30)
Carotenoids and retinoids have several similar biological activities such as antioxidant properties, the inhibition of malignant tumour growth and the induction of apoptosis. Supplementation with carotenoids can affect cell growth and modulate gene expression and immune responses. Epidemiological studies have
A V Rao et al.
Journal of the American College of Nutrition, 19(5), 563-569 (2000-10-07)
Lycopene, a carotenoid without provitamin-A activity, is present in many fruits and vegetables; however, tomatoes and processed tomato products constitute the major source of lycopene in North American diet. Among the carotenoids, lycopene is a major component found in the
Lycopene: potent antioxidant for oral premalignancy and oral cancer
Sonunu, S.; et al.
European Journal of Biomedical AND Pharmaceutical sciences, 2, 135-144 (2015)
Bo-Yi Jhou et al.
Journal of agricultural and food chemistry, 65(32), 6893-6903 (2017-07-21)
NADPH oxidase 4 (NOX4), with the sole function to produce reactive oxygen species (ROS), can be a molecular target for disrupting cancer metastasis. Several studies have indicated that lycopene exhibited anti-metastatic actions in vitro and in vivo. However, the role
Sonia Gupta et al.
International journal of preventive medicine, 6, 70-70 (2015-09-04)
Without pigments, we are nothing. Life presents us with a kaleidoscope of colors. From the green grass of home to a forest's ruddy autumn hues, we are surrounded by living colors. Living things obtain their colors, with few exceptions, from
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