Merck
CN

103284

Sigma-Aldrich

2-甲氧基-5-甲基苯胺

99%

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别名:
5-甲基-邻茴香胺, 6-甲氧基-间甲苯胺, 对甲酚定
线性分子式:
CH3OC6H3(CH3)NH2
CAS号:
分子量:
137.18
Beilstein:
637071
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.22

蒸汽密度

4.7 (vs air)

质量水平

检测方案

99%

形式

solid

bp

235 °C (lit.)

mp

50-52 °C (lit.)

SMILES字符串

COc1ccc(C)cc1N

InChI

1S/C8H11NO/c1-6-3-4-8(10-2)7(9)5-6/h3-5H,9H2,1-2H3

InChI key

WXWCDTXEKCVRRO-UHFFFAOYSA-N

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一般描述

2-Methoxy-5-methylaniline is an aromatic amine present as contaminants in commercial hair dye samples.

应用

2-Methoxy-5-methylaniline was used in the synthesis of 4-(4-Amino-5-methoxy-2-methylphenylazo)-5-hydroxy-naphthalene-2,7-disulfonic acid. 2-Methoxy-5-methylaniline was used to analyse the application of polymeric ionic liquids as selective solid-phase microextraction sorbent coatings for the analysis of genotoxic impurities and structurally alerting compounds such as alkyl halides and aromatics. 2-Methoxy-5-methylaniline was used in a study to develop a sensitive analytical method for the determination of aromatic amines found in commercial hair dyes using high liquid chromatography coupled to an electrochemical detector by using the ionic liquid 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide in the mobile phase.

象形图

Exclamation markHealth hazard

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

230.0 °F - closed cup

闪点(°C)

110 °C - closed cup

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品

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Kannan P Naicker et al.
Bioorganic & medicinal chemistry, 12(5), 1215-1220 (2004-02-26)
A structure-based design approach has been used to optimize a lead HIV-1 entry inhibitor targeted to the envelope glycoprotein gp41. The docking study on this lead compound revealed important structural requirements that need to be preserved as well as structural
Tien D Ho et al.
Journal of chromatography. A, 1240, 29-44 (2012-04-28)
A series of polymeric ionic liquids (PILs) possessing varied chemical makeup and composition were applied as selective solid-phase microextraction (SPME) sorbent coatings for the analysis of genotoxic impurities (GTIs) and related structurally alerting compounds, namely, alkyl halides and aromatics. In
R W Tennant et al.
Carcinogenesis, 14(1), 29-35 (1993-01-01)
Three transgenic mouse lines carrying v-Ha-ras (TG-SH), c-myc (TG-M) or c-neu (TG-NK) oncogenes under regulatory control of mouse mammary tumor virus (MMTV) long terminal repeat (LTR) sequences were evaluated for responses to two chemical carcinogens. p-Cresidine, a mutagenic urinary bladder
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p-Cresidine was administered in the feed at either of two concentrations (0.5 and 1.0 percent) to groups of 50 male and 50 female F344 rats for 104 weeks. Fifty animals of each sex were placed on test as controls and
Thiago Mescoloto Lizier et al.
Molecules (Basel, Switzerland), 17(7), 7961-7979 (2012-07-04)
The room temperature ionic liquid (IL) 1-butyl-3-methylimidazolium bis-(trifluorometanesulfonyl)imide BMIm[NTf₂] was used as a novel medium for improvement of separation and quantization of 16 aromatic amines typically present as contaminants in consumer products and detected by HPLC coupled to an electrochemical

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