107700
4-(二甲氨基)吡啶
ReagentPlus®, ≥99%
别名:
N,N-二甲基-4-吡啶胺, DMAP
等级
reagent grade
质量水平
产品线
ReagentPlus®
方案
≥99%
表单
chips
crystalline powder
flakes
浓度
≤100%
pH值（酸碱度）
(10,23 at -0,1 g/l at 22 °C)
沸点
162 °C
mp
108-110 °C (lit.)
溶解性
H2O: 50 mg/mL
官能团
amine
储存温度
room temp
SMILES字符串
CN(C)c1ccncc1
InChI
1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3
InChI key
VHYFNPMBLIVWCW-UHFFFAOYSA-N
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一般描述
4-二甲氨基吡啶（DMAP）是一种多功能亲核催化剂，用于酰化和酯化反应。它也可用于各种有机转化反应，如Baylis-Hillman反应、Dakin-West反应、胺的保护、C-酰化、硅烷化、天然产物化学中的应用。
应用
4-二甲氨基吡啶可用作以下反应的催化剂：
- 通过与丙二腈、醛和β-硝基烯反应合成3,5 取代的2,6-二氰基苯胺。
- 在无辅助碱和溶剂的条件下与酸酐进行醇的酰化反应合成相应的酯。
- 通过活化烯和醛或酮的偶联进行Baylis-Hillman 反应生成碳碳键。
酰化反应的高效催化剂
法律信息
ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 1
靶器官
Nervous system
储存分类代码
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
闪点(°F)
255.2 °F
闪点(°C)
124 °C
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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