129925
甲基磺酸甲酯
99%
别名:
甲磺酸甲酯
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关于此项目
线性分子式:
CH3SO3CH3
化学文摘社编号:
分子量:
110.13
UNSPSC Code:
12352103
NACRES:
NA.22
PubChem Substance ID:
EC Number:
200-625-0
Beilstein/REAXYS Number:
1098586
MDL number:
Biochem/physiol Actions
DNA 加合物；优先地将甲基加合到 DNA 的 7-鸟嘌呤，也可加合到 3-腺嘌呤和 3-鸟嘌呤。
signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Inhalation
target_organs
Lungs
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
219.2 °F - closed cup
flash_point_c
104 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Cathrine Broberg Vågbø et al.
DNA repair, 12(3), 188-195 (2013-01-02)
Cytotoxic 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) lesions induced in DNA and RNA in vitro and in pre-damaged DNA and RNA bacteriophages in vivo are repaired by the Escherichia coli (E. coli) protein AlkB and a human homolog, ALKBH3. However, it
Stephen Godin et al.
Nucleic acids research, 41(8), 4525-4534 (2013-03-06)
The Saccharomyces cerevisiae Shu complex, consisting of Shu1, Shu2, Csm2 and Psy3, promotes error-free homologous recombination (HR) by an unknown mechanism. Recent structural analysis of two Shu proteins, Csm2 and Psy3, has revealed that these proteins are Rad51 paralogues and
Amaya Azqueta et al.
Toxicology in vitro : an international journal published in association with BIBRA, 27(2), 768-773 (2012-12-25)
A serious limitation of the conventional comet assay (single cell gel electrophoresis) is the restriction on the number of samples that can be processed in one experiment, imposed by the size of the electrophoresis platform. One approach to increasing throughput
Stephanie Jungmichel et al.
Molecular cell, 52(2), 272-285 (2013-09-24)
Poly(ADP-ribos)ylation (PARylation) is a reversible posttranslational modification found in higher eukaryotes. However, little is known about PARylation acceptor proteins. Here, we describe a sensitive proteomics approach based on high-accuracy quantitative mass spectrometry for the identification of PARylated proteins induced under
Shawn Hoon et al.
Nature chemical biology, 4(8), 498-506 (2008-07-16)
Bioactive compounds are widely used to modulate protein function and can serve as important leads for drug development. Identifying the in vivo targets of these compounds remains a challenge. Using yeast, we integrated three genome-wide gene-dosage assays to measure the
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