131040
甲基反丁烯二酸
99%
别名:
甲基富马酸
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线性分子式:
HOOCCH=C(CH3)COOH
化学文摘社编号:
分子量:
130.10
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
207-859-2
Beilstein/REAXYS Number:
1722680
MDL number:
产品名称
甲基反丁烯二酸, 99%
InChI key
HNEGQIOMVPPMNR-NSCUHMNNSA-N
InChI
1S/C5H6O4/c1-3(5(8)9)2-4(6)7/h2H,1H3,(H,6,7)(H,8,9)/b3-2+
SMILES string
C\C(=C/C(O)=O)C(O)=O
assay
99%
form
powder
mp
200-202 °C (lit.)
Quality Level
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Application
- 来自生物质中康酸的可再生异戊二烯的工艺设计和经济学分析：详细介绍了橡胶工业中的关键化学物质异戊二烯的可持续生产方法，该异戊二烯来自源于生物质的中康酸，体现了其与绿色化学和材料科学的相关性（Lundberg et al., 2019）。
- 基于脂肪族连接子中康酸的新型Al-MOF的绿色合成： Al-MIL-68-Mes的结构、性质和原位结晶研究：利用可用于催化、气体储存和分离技术的中康酸考察了新型金属有机框架（MOF）的合成和性质（Reinsch et al., 2018)。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Clinica chimica acta; international journal of clinical chemistry, 110(2-3), 187-203 (1981-03-05)
Two metabolites, 4-hydroxyisovaleric acid and mesaconic acid, have been identified and quantified in the urine of a patient with isovaleric acidemia. These compounds do not appear to have been reported previously as being components of human metabolism. In addition, large
Nicolle H R Litjens et al.
European journal of immunology, 34(2), 565-575 (2004-02-10)
Psoriasis vulgaris, a type-1 cytokine-mediated chronic skin disease, can be treated successfully with fumaric acid esters (FAE). Beneficial effects of this medication coincided with decreased production of IFN-gamma. Since dendritic cells (DC) regulate the differentiation of T helper (Th) cells
G Leschziner et al.
Journal of neurology, 258(8), 1489-1493 (2011-03-03)
We report a case of a patient with a rapidly progressive dementing illness and gait disturbance, in whom initial screening demonstrated a high methylmalonic acid level only, suggestive of a functional vitamin B(12) deficiency. Despite B(12) replacement therapy, he continued
Darius Moharregh-Khiabani et al.
PloS one, 5(7), e11769-e11769 (2010-07-30)
Fumaric acid esters (FAE) are a group of compounds which are currently under investigation as an oral treatment for relapsing-remitting multiple sclerosis. One of the suggested modes of action is the potential of FAE to exert a neuroprotective effect. We
K Asadullah et al.
Archives of dermatological research, 289(11), 623-630 (1998-01-28)
Although the effectiveness of systemic antipsoriatic treatment with fumaric acid esters has been proven, their mode of action is still not understood. Recent results indicate their potency in inducing cytokine production in stimulated T cells. Since monocytes and their cytokines
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