137723
2,4,6-三碘苯酚
97%
别名:
Bobel 24
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关于此项目
线性分子式:
I3C6H2OH
化学文摘社编号:
分子量:
471.80
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
210-186-7
MDL number:
Assay:
97%
Form:
powder
InChI key
VAPDZNUFNKUROY-UHFFFAOYSA-N
InChI
1S/C6H3I3O/c7-3-1-4(8)6(10)5(9)2-3/h1-2,10H
SMILES string
Oc1c(I)cc(I)cc1I
assay
97%
form
powder
mp
157-159 °C (lit.)
functional group
iodo
Quality Level
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General description
2,4,6-三碘苯酚是在污水氯化过程中形成的碘化消毒副产物。它是一种有效的甲状腺激素干扰物。
Application
2,4,6-三碘苯酚被用于人肝微粒体中脱碘酶活性的体外测定。
target_organs
Respiratory system
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Tingting Gong et al.
Chemosphere, 163, 359-365 (2016-08-25)
Iodide is widely present in drinking water sources as well as wastewater effluents. Chlorination and chloramination are the most commonly used disinfection methods. During chlorination or chloramination of drinking water/wastewater effluents, iodide may be oxidized to hypoiodous acid, which may
L Xun et al.
Biochemical and biophysical research communications, 174(1), 43-48 (1991-01-15)
Pentachlorophenol (PCP) degrading Flavobacterium sp. ATCC 39723 was found to degrade other polyhalogenated phenolic compounds, including triiodophenol, tribromophenol, and trichlorophenol. Each compound was able to induce the degradation of the other compounds. A PCP Flavobacterium sp. mutant, F-2, was unable
L García-Capdevila et al.
Journal of chromatography. B, Biomedical sciences and applications, 708(1-2), 169-175 (1998-07-08)
A rapid and simple HPLC method is described for the determination of Bobel-24 (2,4,6-triiodophenol) and other iodinated derivatives in biological samples. The sample preparation was liquid-liquid extraction before injection onto the HPLC system. 2,6-Diiodo-4-methylphenol was used as internal standard. Separation
G J Miroy et al.
Proceedings of the National Academy of Sciences of the United States of America, 93(26), 15051-15056 (1996-12-24)
Transthyretin (TTR) amyloid fibril formation is observed systemically in familial amyloid polyneuropathy and senile systemic amyloidosis and appears to be the causative agent in these diseases. Herein, we demonstrate conclusively that thyroxine (10.8 microM) inhibits TTR fibril formation efficiently in
Matilde Parreño et al.
Cancer research, 68(15), 6313-6323 (2008-08-05)
The poor prognosis of pancreatic cancer and poor sensitivity to current therapeutics, associated with resistance to apoptosis, urge the search for new drugs. We previously described the induction of caspase-independent mithochondrial death in leukemia cells by Bobel-24 (AM-24) and derivatives.
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