14075
琥珀半醛 溶液
~15% in H2O (T)
别名:
4-Oxobutyric acid, 4-氧丁酸, Succinaldehydic acid, 琥珀半醛单体
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关于此项目
线性分子式:
HCOCH2CH2COOH
化学文摘社编号:
分子量:
102.09
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Beilstein/REAXYS Number:
1745187
SMILES string
OC(=O)CCC=O
concentration
~15% in H2O (T)
storage temp.
2-8°C
Other Notes
与 DHAP 发生酶催化羟醛反应；琥珀半醛脱氢酶的底物
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
Berin A Boughton et al.
Proteins, 80(8), 2117-2122 (2012-05-04)
The crystal structure of Escherichia coli dihydrodipicolinate synthase with pyruvate and substrate analogue succinic acid semialdehyde condensed with the active site lysine-161 was solved to a resolution of 2.3 Å. Comparative analysis to a previously reported structure both resolves the
Luiz Pedro S de Carvalho et al.
Archives of biochemistry and biophysics, 509(1), 90-99 (2011-02-10)
Succinic semialdehyde dehydrogenases (SSADHs) are ubiquitous enzymes that catalyze the NAD(P)+-coupled oxidation of succinic semialdehyde (SSA) to succinate, the last step of the γ-aminobutyrate shunt. Mycobacterium tuberculosis encodes two paralogous SSADHs (gabD1 and gabD2). Here, we describe the first mechanistic
Hatice Gökcan et al.
The Journal of organic chemistry, 77(13), 5533-5543 (2012-06-01)
Pyridoxal 5-phosphate (PLP), the phosphorylated and the oxidized form of vitamin B6 is an organic cofactor. PLP forms a Schiff base with the ϵ-amino group of a lysine residue of PLP-dependent enzymes. γ-Aminobutyric acid (GABA) aminotransferase is a PLP-dependent enzyme
Hongzhi Tang et al.
The Journal of biological chemistry, 286(45), 39179-39187 (2011-09-29)
Nicotine, the main alkaloid produced by Nicotiana tabacum and other Solanaceae, is very toxic and may be a leading toxicant causing preventable disease and death, with the rise in global tobacco consumption. Several different microbial pathways of nicotine metabolism have
Jiri Brichac et al.
Chemical research in toxicology, 20(6), 887-895 (2007-05-08)
trans-4-Hydroxy-2-nonenal (HNE) is a cytotoxic alpha,beta-unsaturated aldehyde implicated in the pathology of multiple diseases involving oxidative damage. Oxidation of HNE by aldehyde dehydrogenases (ALDHs) to trans-4-hydroxy-2-nonenoic acid (HNEA) is a major route of metabolism in many organisms. HNE exists as
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