148113
2,6-二氨基甲苯
97%
别名:
2,6-甲苯二胺, 2-甲基间苯二胺, 甲苯-2,6-二胺
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关于此项目
线性分子式:
CH3C6H3(NH2)2
化学文摘社编号:
分子量:
122.17
Beilstein:
2079476
EC 号:
MDL编号:
UNSPSC代码:
12162002
PubChem化学物质编号:
NACRES:
NA.23
方案
97%
表单
solid
mp
104-106 °C (lit.)
SMILES字符串
Cc1c(N)cccc1N
InChI
1S/C7H10N2/c1-5-6(8)3-2-4-7(5)9/h2-4H,8-9H2,1H3
InChI key
RLYCRLGLCUXUPO-UHFFFAOYSA-N
一般描述
2,6-Diaminotoluene (2,6-DAT) is an aromaticamine characterized by its two amino groups located at the 2 and 6 positions ona toluene ring. This structure imparts unique properties such as highreactivity and the ability to form hydrogen bonds, making it an importantintermediate in synthesis thermoplastic polyamides. Its solubility in organicsolvents further enhances its applicability in polymer synthesis of compositepolymer materials and drug delivery systems.
警示用语：
Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Muta. 2 - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
危险化学品
此项目有
M L Cunningham et al.
Environmental health perspectives, 104 Suppl 3, 683-686 (1996-05-01)
The aromatic amines 2,4-diaminotoluene (2,4-DAT) and 2,6-diaminotoluene (2,6-DAT) are structural isomers that have been extensively studied for their mutagenic and carcinogenic characteristics. Both compounds are rapidly absorbed after oral administration and are equally mutagenic in the Ames test; however, 2,4-DAT
Diaminotoluenes induce intrachromosomal recombination and free radicals in Saccharomyces cerevisiae.
R J Brennan et al.
Mutation research, 381(2), 251-258 (1998-01-22)
The carcinogenicity of aniline-based aromatic amines is poorly reflected by their activity in short-term mutagenicity assays such as the Salmonella typhimurium reverse mutation (Ames) assay. More information about the mechanism of action of such carcinogens is needed. Here we report
P Lind et al.
The Analyst, 122(1), 51-56 (1997-01-01)
Blood and urine samples were collected from six workers and two volunteers exposed to thermal degradation products from toluene diisocyanate (TDI)-based polyurethane (PUR) before and during the summer vacation. Air samples were collected on filters impregnated with 9-(N-methylaminomethyl)anthracene. The concentrations
M Taningher et al.
Toxicology, 99(1-2), 1-10 (1995-05-05)
Among aminoaromatics, 2,4-diaminotoluene (2,4-DAT) and 2,6-diaminotoluene (2,6-DAT) represent a conflicting couple of isomers; despite showing the same structural alert to DNA reactivity (and thus potential genotoxicity), they are different in terms of carcinogenicity. Of the two, 2,4-DAT alone is a
Differential in vivo mutagenicity of the carcinogen/non-carcinogen pair 2,4- and 2,6-diaminotoluene.
J J Hayward et al.
Carcinogenesis, 16(10), 2429-2433 (1995-10-01)
The aromatic amines 2,4-diaminotoluene (2,4-DAT) and 2,6-diaminotoluene (2,6-DAT) are structural isomers that have been extensively studied for their mutagenic and carcinogenic characteristics. Both compounds are equally mutagenic in the Ames/Salmonella assay in the presence of S9. However, the differences in
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