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Merck
CN

15149

N,N-双(膦羟甲基)甘氨酸

≥98.0% (T)

别名:

增甘磷

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关于此项目

经验公式(希尔记法):
C4H11NO8P2
化学文摘社编号:
分子量:
263.08
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
219-468-4
Beilstein/REAXYS Number:
1884944
MDL number:
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产品名称

N,N-双(膦羟甲基)甘氨酸, ≥98.0% (T)

InChI key

OXHDYFKENBXUEM-UHFFFAOYSA-N

InChI

1S/C4H11NO8P2/c6-4(7)1-5(2-14(8,9)10)3-15(11,12)13/h1-3H2,(H,6,7)(H2,8,9,10)(H2,11,12,13)

SMILES string

O=P(CN(CP(O)(O)=O)CC(O)=O)(O)O

assay

≥98.0% (T)

functional group

amine
carboxylic acid

Quality Level

General description

N,N-Bis(phosphonomethyl)glycine was present in the ligand bound to human apotransferrin.

Application

络合剂;pK 值:pK1:≤2,pK2:2.0,pK3:5.20,pK4:6.77,pK5:10.89

Biochem/physiol Actions

Anti-diabetic; delay onset of diabetes in non-obese NOD mice

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

农药列管产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Aurelia Visa et al.
Nanomaterials (Basel, Switzerland), 10(5) (2020-05-14)
The rapid increase of industrial activities leads to serious environmental pollution, especially, in aqueous systems and particularly with heavy metals. Cadmium, one of the most poisonous elements, is rapidly accumulated in the human body, therefore, the efficient removal of cadmium
Eva Orejuela et al.
Electrophoresis, 26(23), 4478-4485 (2005-11-01)
A straightforward and sensitive method has been developed for the analysis of phosphorus-containing amino acid herbicides (glufosinate and aminomethylphosphonic acid, the major metabolite of glyphosate) in soil samples. For this purpose, the analytical features of two indocyanine fluorescent dyes, sulfoindocyanine
Aaron W Michels et al.
Journal of immunology (Baltimore, Md. : 1950), 187(11), 5921-5930 (2011-11-02)
Class II major histocompatibility molecules are the primary susceptibility locus for many autoimmune disorders, including type 1 diabetes. Human DQ8 and I-A(g7), in the NOD mouse model of spontaneous autoimmune diabetes, confers diabetes risk by modulating presentation of specific islet
L J Olson et al.
Toxicology, 30(2), 103-114 (1984-03-01)
Exposure to the plant growth regulators, chlorocholine chloride (CCC) and glyphosine (GPS), resulted in significant immunomodulatory effects after feeding to deer mice (Peromyscus maniculatus) for 28 days. Cyclophosphamide (CP) and saline controls were included. Both CCC and GPS feeding levels
W R Harris et al.
Biochemistry, 30(28), 6930-6936 (1991-07-16)
Difference ultraviolet spectroscopy has been used to monitor the binding of a series of phosphonate ligands to human apotransferrin. The ligands consist of pyrophosphate as well as the phosphonic acids (aminomethyl)phosphonic acid (AMPA), (hydroxymethyl)phosphonic acid (HMP), (phosphonomethyl)-iminodiacetic acid (PIDA), N,N-bis(phosphonomethyl)glycine

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