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文件

160660

喹哪啶酸

Name: 喹哪啶酸
Brand: ALDRICH

98%

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别名:

2-喹啉羧酸

经验公式（希尔记法）:

C₁₀H₇NO₂

CAS号:

93-10-7

分子量:

173.17

Beilstein:

126322

EC 号:

202-218-3

MDL编号:

MFCD00006752

PubChem化学物质编号:

24849884

NACRES:

NA.22

检测方案

98%

形式

solid

mp

156-158 °C (lit.)

SMILES string

OC(=O)c1ccc2ccccc2n1

InChI

1S/C10H7NO2/c12-10(13)9-6-5-7-3-1-2-4-8(7)11-9/h1-6H,(H,12,13)

InChI key

LOAUVZALPPNFOQ-UHFFFAOYSA-N

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一般描述

喹啉酸也称为喹啉-2-羧酸。已报告微波辅助合成喹啉酸取代苯胺的方法。抑制丙酮酸盐的氧化，α-大鼠肝线粒体中的酮戊二酸、谷氨酸和柠檬酸。喹啉酸是色氨酸降解的代谢产物，抑制灌注肝脏中的糖异生。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

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705578-5MG-PW

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1000309185

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Deciphering the biosynthesis pathway of the antitumor thiocoraline from a marine actinomycete and its expression in two streptomyces species.

Felipe Lombó et al.

Chembiochem : a European journal of chemical biology, 7(2), 366-376 (2006-01-13)

Thiocoraline is a thiodepsipeptide antitumor compound produced by two actinomycetes Micromonospora sp. ACM2-092 and Micromonospora sp. ML1, isolated from two marine invertebrates (a soft coral and a mollusc) found of the Indian Ocean coast of Mozambique. By using oligoprimers derived

Transcriptional response pathways in a yeast strain sensitive to saframycin a and a more potent analog: evidence for a common basis of activity.

Alleyn T Plowright et al.

Chemistry & biology, 9(5), 607-618 (2002-05-29)

Saframycin A (SafA) is a natural product that inhibits human cancer cell proliferation. Its synthetic analog, QAD, is a more potent inhibitor of these cells. SafA does not affect wild-type yeast, but it does inhibit growth of the strain CCY333

Positive selection for loss of tetracycline resistance.

B R Bochner et al.

Journal of bacteriology, 143(2), 926-933 (1980-08-01)

A simple technique has been devised that allows direct plate selection of tetracycline-sensitive clones from a predominantly tetracycline-resistant population. The technique is especially useful in genetic methodologies based on the use of tetracycline resistance transposons, such as Tn10. Potential uses

Microwave-assisted synthesis of new substituted anilides of quinaldic acid.

Pavel Bobal et al.

Molecules (Basel, Switzerland), 17(2), 1292-1306 (2012-02-02)

In this study a one step method for the preparation of substituted anilides of quinoline-2-carboxylic acid was developed. This efficient innovative approach is based on the direct reaction of an acid or ester with substituted anilines using microwave irradiation. The

Stereocontrolled synthesis of the quinaldic acid macrocyclic system of thiostrepton.

K C Nicolaou et al.

Angewandte Chemie (International ed. in English), 41(11), 1937-1940 (2002-06-03)

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