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Merck
CN

161543

Sigma-Aldrich

5-(4-羟基苯基)-5-苯基乙内酰脲

98%

别名:

4-Hydroxydiphenylhydantoin, p-Hydroxyphenytoin, NSC 156081

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About This Item

经验公式(希尔记法):
C15H12N2O3
CAS Number:
分子量:
268.27
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22

方案

98%

表单

solid

mp

>300 °C (lit.)

溶解性

soluble 50 mg/mL, clear, colorless to faintly yellow (DMF:MeOH(2:1))

官能团

phenyl

SMILES字符串

Oc1ccc(cc1)C2(NC(=O)NC2=O)c3ccccc3

InChI

1S/C15H12N2O3/c18-12-8-6-11(7-9-12)15(10-4-2-1-3-5-10)13(19)16-14(20)17-15/h1-9,18H,(H2,16,17,19,20)

InChI key

XEEDURHPFVXALT-UHFFFAOYSA-N

一般描述

5-(4-Hydroxyphenyl)-5-phenylhydantoin is the major metabolite of phenytoin.

应用

5-(4-Hydroxyphenyl)-5-phenylhydantoin was used in enantiomeric separation of chiral pharmaceuticals using a teicoplanin chiral stationary phase by aqueous and non-aqueous packed capillary electrochromatography. It was used as internal standard in determination of phenylbutazone and its metabolite oxyphenbutazone in human plasma by GLC.
Reactant for activation of hydroxylated metabolites of carbamazepine and phenytoin

Used in studies investigating
Transport across the human placenta barrier
Effects on cellular glucose transport

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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