179000
1,4-苯并二噁烷
97%
别名:
1,2-乙烯基二氧苯, 1,4-Benzodioxan, 1,4-苯并二氧六环
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关于此项目
经验公式（希尔记法）:
C8H8O2
化学文摘社编号:
分子量:
136.15
UNSPSC Code:
12352100
NACRES:
NA.21
PubChem Substance ID:
EC Number:
207-775-6
Beilstein/REAXYS Number:
120846
MDL number:
Application
Benzo-1,4-dioxane (2,3-dihydro-1,4-benzodioxin) was used in the synthesis of stereoisomers which were evaluated as α- and β- adrenergic antagonists.
General description
The anti-inflammamtory properties and synthesis of carboxylic acid compounds containing benzo-1,4-dioxane (2,3-dihydro-1,4-benzodioxin) subunit was studied.
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 3
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
156.2 °F - closed cup
flash_point_c
69 °C - closed cup
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
M T Vázquez et al.
Farmaco (Societa chimica italiana : 1989), 51(3), 215-217 (1996-03-01)
Synthesis and antiinflammatory properties of new carboxylic acids containing the 2,3-dihydro-1,4-benzodioxin subunit are described. The 2-(2,3-dihydro-1, 4-benzodioxin-6-yl)acetic acid was of comparable potency to Ibuprofen, in carrageenan induced rat paw edema assay.
M Khouili et al.
Farmaco (Societa chimica italiana : 1989), 51(3), 185-188 (1996-03-01)
The four stereoisomers of compound 1 were synthesized from 2,3-dihydro-1, 4-benzodioxin and evaluated as alpha- and beta-adrenergic antagonists. Enantiomer 1-b [2R, 2'S] (Figure 1) is the best beta 1-blocking agent. Furthermore all compounds showed a alpha-blocking activity.
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