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Merck
CN

189162

Sigma-Aldrich

2-甲氧基-1,4-萘醌

98%

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关于此项目

经验公式(希尔记法):
C11H8O3
化学文摘社编号:
分子量:
188.18
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.22
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方案

98%

mp

184-187 °C (lit.)

官能团

ether
ketone

SMILES字符串

COC1=CC(=O)c2ccccc2C1=O

InChI

1S/C11H8O3/c1-14-10-6-9(12)7-4-2-3-5-8(7)11(10)13/h2-6H,1H3

InChI key

OBGBGHKYJAOXRR-UHFFFAOYSA-N

一般描述

2-甲氧基-1,4-萘醌是“幽门螺杆菌感染相关疾病治疗”的潜在候选药物。它是从凤仙的叶中分离得到的。

应用

2-甲氧基-1,4-萘醌用于制备2-(4-X-亚苯基)胺-1,4-萘醌(X =二茂铁基,OMe,Me,I,Cl和NO2

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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K Ishiguro et al.
Journal of natural products, 61(9), 1126-1129 (1998-09-28)
Dinaphthofuran-7,12-dione derivatives named balsaminones A (1) and B (2) were isolated from the pericarp of Impatiens balsamina L. together with the known compound 2-methoxy-1,4-naphthoquinone (3). Their structures were elucidated by spectral techniques. These compounds have significant antipruritic activity.
Nattapon Sritrairat et al.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 40(1), 90-96 (2010-08-27)
The aim of this study was to determine the antifungal activity of lawsone methyl ether mouthwash (LME) in comparison with chlorhexidine mouthwash (CHX) in vitro and in vivo. For in vitro study, each mouthwash preparation was added into the inoculum
Scott B Vafai et al.
PloS one, 11(9), e0162686-e0162686 (2016-09-14)
Deficiency of mitochondrial complex I is encountered in both rare and common diseases, but we have limited therapeutic options to treat this lesion to the oxidative phosphorylation system (OXPHOS). Idebenone and menadione are redox-active molecules capable of rescuing OXPHOS activity
Martin J Mitchell et al.
Archives of insect biochemistry and physiology, 66(1), 45-52 (2007-08-21)
The effects of the natural compound 2-methoxy-1,4-naphthoquinone, isolated from the leaves of Impatiens glandulifera and the synthetic compounds 2-propoxy-1,4-naphthoquinone and 2-isopropoxy-1,4-naphthoquinone on ecdysone 20-monooxygenase (E-20-M) activity were examined in three insect species. Homogenates of wandering stage third instar larvae of
S Rodriguez et al.
Planta medica, 61(4), 362-364 (1995-08-01)
A chemical and biological screening of 25 species of the Gentianaceae family has been undertaken. Both methanolic and dichloromethane extracts of Swertia calycina exhibited a strong antifungal activity against Cladosporium cucumerinum and Candida albicans. The compound responsible for this activity

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