Quality Level
assay
98%
mp
184-187 °C (lit.)
functional group
ether, ketone
SMILES string
COC1=CC(=O)c2ccccc2C1=O
InChI
1S/C11H8O3/c1-14-10-6-9(12)7-4-2-3-5-8(7)11(10)13/h2-6H,1H3
InChI key
OBGBGHKYJAOXRR-UHFFFAOYSA-N
General description
2-甲氧基-1,4-萘醌是“幽门螺杆菌感染相关疾病治疗”的潜在候选药物。它是从凤仙的叶中分离得到的。
Application
2-甲氧基-1,4-萘醌用于制备2-（4-X-亚苯基）胺-1,4-萘醌（X =二茂铁基，OMe，Me，I，Cl和NO2）。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Yuan-Chuen Wang et al.
Fitoterapia, 83(8), 1336-1344 (2012-04-21)
2-Methoxy-1,4-naphthoquinone (MeONQ) from Impatiens balsamina L. exhibited strong anti-H. pylori activity in our previous study. In this study, we investigated the cytotoxicity of MeONQ against gastric adenocarcinoma (MKN45 cell line) and propose the relevant mechanisms. MeONQ resulted in serious necrosis
X Yang et al.
Phytotherapy research : PTR, 15(8), 676-680 (2001-12-18)
By using brine shrimp (Artemia salina) lethality test-guided fractionation, a single bioactive compound (LC(50)=26 ppm) was isolated from the 95% ethanol extract of the dried aerial parts of Impatiens balsamina L. and subsequently identified as 2-methoxy-1,4-naphthoquinone (MNQ). The structure of
Naomi Mori et al.
Journal of natural medicines, 65(1), 234-236 (2010-10-05)
A screening study using a luciferase assay to identify natural products which inhibit Wnt signaling was carried out. The bioassay-guided fractionation of aerial parts of a plant, Impatiens balsamina, led to the isolation of 2-methoxy-1,4-naphthoquinone (1) as an active compound.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 189162-5G | 04061838759054 |