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Merck
CN

190616

2-羟基-3-硝基吡啶

98%

别名:

3-硝基-2-吡啶酮, 3-硝基-2-吡啶醇

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关于此项目

经验公式(希尔记法):
C5H4N2O3
化学文摘社编号:
分子量:
140.10
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
228-709-2
Beilstein/REAXYS Number:
124474
MDL number:
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assay

98%

mp

212 °C (dec.) (lit.)

SMILES string

Oc1ncccc1[N+]([O-])=O

InChI

1S/C5H4N2O3/c8-5-4(7(9)10)2-1-3-6-5/h1-3H,(H,6,8)

InChI key

BOAFCICMVMFLIT-UHFFFAOYSA-N

General description

2-Hydroxy-3-nitropyridine reacts with phosphorus pentachloride and phosphoryl chloride to yield 2-chloro-3-nitropyridine.

Application

2-Hydroxy-3-nitropyridine was used in the synthesis of:
  • 3-nitro-2-pyridyl β-D-galactoside
  • 3-nitro-2-pyridyl N-acetyl-β-D-glucosaminide
  • 5-amino-6-chloro-3-iodopyridine


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Nitropyridyl glycosides: new glycosyl donors for enzymatic transglycosylation.
Yasukochi T, et al.
Tetrahedron Letters, 40(36), 6585-6589 (1999)
Nanjing Zhang et al.
Bioorganic & medicinal chemistry letters, 13(3), 525-527 (2003-02-05)
Racemic 5-azidoepibatidine [(+/-)-1] was synthesized via 5-aminoepibatidine as a candidate photoaffinity ligand with exceptionally high affinity at the mammalian neuronal nicotinic receptors (K(i) values of 0.027 nM for alpha 4 beta 2 and 9.7 nM for alpha 7) and excellent
85. Nucleophilic displacement reactions in aromatic systems. Part I. Kinetics of the reactions of chloronitropyridines with aromatic amines and with pyridine.
Bishop RR, et al.
Journal of the Chemical Society, 437-446 (1952)