方案
99%
mp
221 °C (dec.) (lit.)
官能团
amine
ketone
SMILES字符串
Cl[H].Cl[H].NCCC(=O)CN
InChI
1S/C4H10N2O.2ClH/c5-2-1-4(7)3-6;;/h1-3,5-6H2;2*1H
InChI key
HDRKYQXFDHZZOW-UHFFFAOYSA-N
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应用
1,4-Diamino-2-butanone dihydrochloride was used as a media supplement for the growth of B.pertussis and B. bronchiseptica.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
D Guzmán-de-Peña et al.
Fungal genetics and biology : FG & B, 21(2), 198-205 (1997-04-01)
Regulation of aflatoxin biosynthesis during differentiation of Aspergillus parasiticus was analyzed by using a drug that inhibits the development of the fungus and mutants affected in sporulation. Diaminobutanone, a competitive inhibitor of ornithine decarboxylase, repressed spore germination. If added after
D Menezes et al.
Parasitology research, 98(2), 99-105 (2005-11-12)
Trypanosoma cruzi is the etiological agent of American trypanosomiasis. Most of the available data on trypanosomatid parasites were obtained from African trypanosomes. Parasitic protozoa polyamine metabolism and transport pathways comprise valuable targets for chemotherapy. T. cruzi cannot synthesize putrescine, but
A G Tkachenko et al.
Mikrobiologiia, 70(4), 487-494 (2001-09-18)
The level of expression of oxyR, the gene that protects Escherichia coli against oxidative stress, was enhanced by physiological concentrations of the biogenic amine putrescine. This level was directly proportional to the degree of negative DNA supercoiling. 1,4-Diamino-2-butanone (DAB), a
Yukihiro Ueno et al.
Biological & pharmaceutical bulletin, 27(6), 890-892 (2004-06-10)
Candida albicans generally grows in hyphae form in RPMI1640 medium. However, addition of 1,4-diamino-2-butanone (DAB), a competitive inhibitor of ornithine decarboxylase, decreased the amount of polyamines in C. albicans, and induced the proliferation of the C. albicans yeast form. The
A G Tkachenko et al.
Biochemistry. Biokhimiia, 72(1), 109-116 (2007-02-21)
Mechanisms of antioxidant effect of polyamines were studied in dependence on the strength of superoxide stress. Under conditions of weak stress, polyamines from Escherichia coli cultures were shown to function mainly as a scavenger of free superoxide radicals, whereas under
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