方案
97%
InChI
1S/C10H16N2O2.H2O4S.H2O/c11-9-1-3-10(4-2-9)12(5-7-13)6-8-14;1-5(2,3)4;/h1-4,13-14H,5-8,11H2;(H2,1,2,3,4);1H2
InChI key
ZWZDWBQKZSSBNM-UHFFFAOYSA-N
Peter J Frosch et al.
Contact dermatitis, 65(2), 96-100 (2011-05-07)
Adverse reactions to permanent hair dyes are frequent, and primarily result from sensitization to p-phenylenediamine (PPD). To investigate the degree of cross-reactivity to a chemically similar dye, hydroxyethyl-p-phenylenediamine sulfate (HPPS), and whether this might be a dyeing alternative for patients
A Hagiwara et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 34(6), 537-546 (1996-06-01)
2,2'-[(4-aminophenyl)imino]bisethanol sulfate (4APE) was administered at dietary levels of 0 (control), 300, 1000 and 3000 ppm to groups of 50 male and 50 female Fischer 344/DuCrj rats for 104 wk. As slight body weight retardation was observed in the male
A Hagiwara et al.
The Journal of toxicological sciences, 14(2), 77-86 (1989-05-01)
The modifying effects of 2,2'-[(4-aminophenyl) imino] bisethanol sulfate (4APE) on liver carcinogenesis were investigated in male F344/DuCrj rats initially treated with N-nitrosodiethylamine (DEN). Two weeks after a single dose of DEN (200 mg/kg, intraperitoneally), rats were given 4APE at dietary
C M Burnett et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 24(8), 875-880 (1986-08-01)
N,N-Bis-(2-hydroxyethyl)-p-phenylenediamine sulphate (N,N-Bis) was administered to 40 male and 45 female Sprague-Dawley rats per group by admixture with their diets at levels of 0.03, 0.1 and 0.3% for periods up to 6 months. Methaemoglobin levels were determined at wk 6.
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