22550
2-甲基喹啉
≥95.0% (GC)
别名:
喹哪啶
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关于此项目
经验公式（希尔记法）:
C10H9N
化学文摘社编号:
分子量:
143.19
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
202-085-1
Beilstein/REAXYS Number:
110309
MDL number:
Assay:
≥95.0% (GC)
Form:
liquid
InChI key
SMUQFGGVLNAIOZ-UHFFFAOYSA-N
InChI
1S/C10H9N/c1-8-6-7-9-4-2-3-5-10(9)11-8/h2-7H,1H3
SMILES string
Cc1ccc2ccccc2n1
assay
≥95.0% (GC)
form
liquid
refractive index
n20/D 1.612 (lit.)
bp
105-107 °C/10 mmHg (lit.), 248 °C (lit.)
mp
−9-−3 °C (lit.)
solubility
chloroform: soluble(lit.), diethyl ether: soluble(lit.), water: insoluble(lit.)
density
1.058 g/mL at 25 °C (lit.)
Gene Information
human ... CYP1A2(1544)
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General description
喹哪啶是一种有机化合物，由巴豆醛和苯胺在脱氢剂存在下与硫酸通过 Skraup 方法制备。以喹那啶为原料合成了几种染料，包括三聚辛氰染料、频哪腈染料、乙烯基染料、喹啉酮染料和喹那啶红。此外，它还用于生产药品、pH 指示剂、食品着色剂、油溶性染料和其他化合物。
Application
喹哪啶可用于：
- 在方胺染料（喹哪啶基方胺染料）的制备中，方胺染料具有重要的生物学意义，可作为金属离子传感器。
- 制备 pH 敏感的比色化学传感器。
Features and Benefits
2-甲基喹啉是可生物降解的。
Disclaimer
储存后可能变为棕色
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
174.2 °F - closed cup
flash_point_c
79 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
危险化学品
此项目有
M Naoi et al.
Life sciences, 40(11), 1075-1082 (1987-03-16)
Type A monoamine oxidase (MAO-A) in human placental mitochondria was competitively inhibited by naturally occurring substances, quinoline and quinaldine, using kynuramine as substrate. Quinoline had a higher affinity for MAO than kynuramine. MAO-A in human brain synaptosomal mitochondria was also
J Ortuño et al.
Fish & shellfish immunology, 12(1), 49-59 (2002-02-28)
Anaesthesia may depress the immune system in mammals, but there is no available information on this topic in fish. In the present work, four anaesthetics that are used in aquaculture, MS222 (0 19 mM), benzocaine (0.21 mM), 2-phenoxyethanol (16 mM)
Yongmei Li et al.
Journal of hazardous materials, 173(1-3), 151-158 (2009-09-08)
The anaerobic degradation of quinoline, isoquinoline and 2-methylquinoline was investigated under nitrate-reducing conditions with acclimated activated sludge. Quinoline was completely transformed during degradation with an optimum COD/NO(3)-N ratio of 7. Isoquinoline and 2-methylquinoline were also completely transformed; however, nitrate consumption
Sumaira Khan et al.
Talanta, 80(1), 158-162 (2009-09-29)
A separation/preconcentration of aluminum (III) (Al(3+)) has been developed to overcome the problem of high matrix species, which may interfere with the determination of trace quantity of Al(3+) in natural water samples. The separation of Al(3+) in water samples was
Antonello Mai et al.
Journal of medicinal chemistry, 49(23), 6897-6907 (2006-12-13)
Starting from a yeast phenotypic screening performed on 21 compounds, we described the identification of two small molecules (9 and 18) able to significantly reduce the S. cerevisiae cell growth, thus miming the effect of GCN5 deletion mutant. Tested on
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