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Merck
CN

242357

二溴乙酸

97%

别名:

2,2-二溴乙酸, DBAA

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线性分子式:
Br2CHCOOH
化学文摘社编号:
分子量:
217.84
UNSPSC Code:
12352106
NACRES:
NA.22
PubChem Substance ID:
EC Number:
211-165-5
Beilstein/REAXYS Number:
1700457
MDL number:
Assay:
97%
Form:
solid
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产品名称

二溴乙酸, 97%

InChI key

SIEILFNCEFEENQ-UHFFFAOYSA-N

InChI

1S/C2H2Br2O2/c3-1(4)2(5)6/h1H,(H,5,6)

SMILES string

OC(=O)C(Br)Br

assay

97%

form

solid

bp

128-130 °C/16 mmHg (lit.)

mp

32-38 °C (lit.)

density

2.382 g/mL at 25 °C (lit.)

functional group

bromo
carboxylic acid

Quality Level

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相关类别

Application

二溴乙酸可用作以下反应的反应物:
  • 通过与醛进行二碘化钐(SmI2) 催化的反应进行(E)-α, β-不饱和羧酸的立体选择性合成。
  • 在NaOH存在的情况下与2-巯基吡啶反应合成双(2-吡啶硫代基)乙酸钠。

Other Notes

残留物为一溴乙酸

pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Wenbo Jiang et al.
Metabolic brain disease, 32(6), 2009-2019 (2017-08-28)
Dibromoacetic acid (DBA) exsits in drinking water as a by-product of disinfection as a result of chlorination or ozonation processes. Hippocampus and pre-frontal cortex are the key structures in memory formation and weanling babies are more sensitive to environmental toxicant
N M Weber et al.
Toxicological sciences : an official journal of the Society of Toxicology, 89(1), 325-330 (2005-10-14)
Water disinfection by-products, such as dibromoacetic acid (DBA), are formed when drinking water is treated with chlorination, bromination, or ozonation. Epidemiological studies have linked these byproducts to adverse effects in humans such as cancer, developmental defects, and reproductive toxicities. DBA
K J Bodensteiner et al.
Toxicological sciences : an official journal of the Society of Toxicology, 80(1), 83-91 (2004-05-14)
To determine if dibromoacetic acid (DBA) affects ovarian folliculogenesis, four groups of female Dutch-belted rabbits were exposed daily to 0, 1, 5, or 50 mg DBA/kg body weight in drinking water beginning in utero from gestation day 15 throughout life.
Ronald L Melnick et al.
Toxicology, 230(2-3), 126-136 (2006-12-13)
Dibromoacetic acid (DBA) is a water disinfection byproduct formed by the reaction of chlorine oxidizing compounds with natural organic matter in water containing bromide. Male and female F344/N rats and B6C3F(1) mice were exposed to DBA in drinking water for
Shuying Gao et al.
Toxicological sciences : an official journal of the Society of Toxicology, 105(2), 331-341 (2008-07-17)
Dibromoacetic acid (DBA) is a haloacetic acid that is present in drinking water as a by-product of chlorinated disinfection. To evaluate its potential adverse health effects, the immunotoxicological effects of DBA on the thymus and spleen of BALB/c mice were

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