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Merck
CN

242357

Sigma-Aldrich

二溴乙酸

97%

别名:

2,2-二溴乙酸, DBAA

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线性分子式:
Br2CHCOOH
化学文摘社编号:
分子量:
217.84
Beilstein:
1700457
EC 号:
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
NACRES:
NA.22
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质量水平

方案

97%

表单

solid

沸点

128-130 °C/16 mmHg (lit.)

mp

32-38 °C (lit.)

密度

2.382 g/mL at 25 °C (lit.)

官能团

bromo
carboxylic acid

SMILES字符串

OC(=O)C(Br)Br

InChI

1S/C2H2Br2O2/c3-1(4)2(5)6/h1H,(H,5,6)

InChI key

SIEILFNCEFEENQ-UHFFFAOYSA-N

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相关类别

应用

二溴乙酸可用作以下反应的反应物:
  • 通过与醛进行二碘化钐(SmI2) 催化的反应进行(E)-α, β-不饱和羧酸的立体选择性合成。
  • 在NaOH存在的情况下与2-巯基吡啶反应合成双(2-吡啶硫代基)乙酸钠。

其他说明

残留物为一溴乙酸

象形图

CorrosionExclamation mark

警示用语:

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 3

闪点(°F)

235.4 °F - closed cup

闪点(°C)

113 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Wenbo Jiang et al.
Metabolic brain disease, 32(6), 2009-2019 (2017-08-28)
Dibromoacetic acid (DBA) exsits in drinking water as a by-product of disinfection as a result of chlorination or ozonation processes. Hippocampus and pre-frontal cortex are the key structures in memory formation and weanling babies are more sensitive to environmental toxicant
Lianhui Tao et al.
Toxicological sciences : an official journal of the Society of Toxicology, 82(1), 62-69 (2004-09-03)
Dibromoacetic acid (DBA) is a drinking water disinfection by-product. Its analogs, dichloroacetic acid (DCA) and trichloroacetic acid (TCA), are liver carcinogens in rodents. We evaluated the ability of DBA to cause DNA hypomethylation, glycogen accumulation, and peroxisome proliferation that are
Gary R Klinefelter et al.
Toxicological sciences : an official journal of the Society of Toxicology, 81(2), 419-429 (2004-07-16)
Previously our work on the haloacid by-products of drinking water disinfection focused on adult exposures. Herein we evaluate the consequence of continuous exposure to dibromoacetic acid (DBA) via drinking water through reproductive development into adulthood. An initial study in which
Ronald L Melnick et al.
Toxicology, 230(2-3), 126-136 (2006-12-13)
Dibromoacetic acid (DBA) is a water disinfection byproduct formed by the reaction of chlorine oxidizing compounds with natural organic matter in water containing bromide. Male and female F344/N rats and B6C3F(1) mice were exposed to DBA in drinking water for
Lianhui Tao et al.
Toxicological sciences : an official journal of the Society of Toxicology, 87(2), 344-352 (2005-07-15)
Bromodichloromethane (BDCM), chloroform, dibromoacetic acid (DBA), dichloroacetic acid (DCA), and trichloroacetic acid (TCA) are chlorine disinfection by-products (DBPs) found in drinking water that have indicated renal carcinogenic and/or tumor promoting activity. We have reported that the DBPs caused DNA hypomethylation

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