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274186

4-氨基苯甲酸甲酯

Name: 4-氨基苯甲酸甲酯
Brand: ALDRICH

98%

别名:

4-(甲酯基)苯胺, 4-氨基苯甲酸甲酯, 对氨基苯甲酸甲酯, 对甲氧基苯胺, 甲基苯胺-4-羧酸酯, （4-（甲酯基）苯基）胺

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关于此项目

线性分子式:

H₂NC₆H₄CO₂CH₃

化学文摘社编号:

619-45-4

分子量:

151.16

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24856569

EC Number:

210-598-7

Beilstein/REAXYS Number:

775913

MDL number:

MFCD00007891

Assay:

98%

Form:

solid

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属性

Quality Level

100

assay

98%

form

solid

mp

110-111 °C (lit.)

functional group

ester

SMILES string

COC(=O)c1ccc(N)cc1

InChI

1S/C8H9NO2/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5H,9H2,1H3

InChI key

LZXXNPOYQCLXRS-UHFFFAOYSA-N

说明

General description

研究了过氧化氢对 4-氨基苯甲酸甲酯的催化氧化。

Application

4-氨基苯甲酸甲酯用于通过质子酸催化的杂 Diels-Alder 与 N-Cbz 2-吡咯啉的偶联反应合成胍生物碱、（±）-马二碱和（±）-马来酸。

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Formulation factors affecting release of drug from topical vehicles. II. Effect of solubility on in vitro delivery of a series of n-alkyl p-aminobenzoates.

C B Lalor et al.

Journal of pharmaceutical sciences, 84(6), 673-676 (1995-06-01)

The major influence on the rate of drug transfer out of its vehicle and into the skin is the thermodynamic activity of the drug within its formulation. This study addresses certain thermodynamic dependencies of topical delivery in a model system.

Processing grapefruit juice with γ-cyclodextrin attenuates its inhibitory effect on cytochrome P450 3A activity.

Keishi Yamasaki et al.

The Journal of pharmacy and pharmacology, 72(3), 356-363 (2019-12-13)

Grapefruit (Citrus paradisi) juice enhances the oral bioavailability of drugs that are metabolized by intestinal cytochrome P450 3A4 (CYP3A4). Patients are advised to avoid drinking grapefruit juice to prevent this drug-grapefruit juice interaction. The aim of this study was to

Topical drug delivery from thin applications: theoretical predictions and experimental results.

W Addicks et al.

Pharmaceutical research, 7(10), 1048-1054 (1990-10-01)

Stainless-steel templates of various thicknesses (75, 200, 800, and 1600 microns) were used to apply propylene glycol/water gels containing methyl or propyl p-aminobenzoates to silicone rubber membranes, and drug delivery was studied with the use of the Bronaugh diffusion cell

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全球贸易项目编号

货号	GTIN
483761-1G	04061832390178
274186-100G	04061838348340
274186-5G	04061826151884
274186-25G	04061826151877