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275034

9,10-菲醌

Name: 9,10-菲醌
Brand: ALDRICH

95%

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别名:

9,10-菲二酮

经验公式（希尔记法）:

C₁₄H₈O₂

CAS号:

84-11-7

分子量:

208.21

Beilstein:

608838

EC 号:

201-515-5

MDL编号:

MFCD00001163

PubChem化学物质编号:

24856622

NACRES:

NA.23

质量水平

100

检测方案

95%

形式

powder

mp

209-212 °C (lit.)

SMILES字符串

O=C1C(=O)c2ccccc2-c3ccccc13

InChI

1S/C14H8O2/c15-13-11-7-3-1-5-9(11)10-6-2-4-8-12(10)14(13)16/h1-8H

InChI key

YYVYAPXYZVYDHN-UHFFFAOYSA-N

基因信息

human ... PTPN1(5770) , PTPRC(5788)

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一般描述

多环芳烃的醌类在所有燃烧的有机物质中含量丰富。在用于钝化硅表面时，它通过杂原子 Diels-Alder 反应与表面上的悬挂键发生反应。因为 π-电子共轭，硅的半导体性质不受影响。

应用

9,10-菲醌可用于在硅 (100) 表面进行高质量钝化。醌类可作为多种黄酶的底物。

象形图

GHS07,GHS09

警示用语：

Warning

危险声明

H319 - H400

预防措施声明

P264 - P273 - P280 - P305 + P351 + P338 - P337 + P313 - P391

危险分类

Aquatic Acute 1 - Eye Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

473.0 °F

闪点(°C)

245 °C

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

分析证书(COA)

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示例

T1503

货号

25G

包装规格/数量

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705578-5MG-PW

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Mutagenicity of quinones: pathways of metabolic activation and detoxification.

P L Chesis et al.

Proceedings of the National Academy of Sciences of the United States of America, 81(6), 1696-1700 (1984-03-01)

The mutagenicity of various quinones, a class of compounds widely distributed in nature, is demonstrated in the Salmonella TA104 tester strain. The metabolic pathways by which four quinones, menadione, benzo[a]pyrene 3,6-quinone, 9,10-phenanthrenequinone, and danthron, caused mutagenicity in this test system

Electronic structure and band alignment of 9, 10-phenanthrenequinone passivated silicon surfaces

Avasthi, Sushobhan, et al.

Surface Science, 605(13), 1308-1312 (2011)

Aldo-keto reductase 1C15 as a quinone reductase in rat endothelial cell: its involvement in redox cycling of 9,10-phenanthrenequinone.

Toshiyuki Matsunaga et al.

Free radical research, 45(7), 848-857 (2011-06-01)

9,10-Phenanthrenequinone (9,10-PQ), a redox-active quinone in diesel exhausts, triggers cellular apoptosis via reactive oxygen species (ROS) generation in its redox cycling. This study found that induction of CCAAT/enhancer-binding protein-homologous protein (CHOP), a pro-apoptotic factor derived from endoplasmic reticulum stress, participates

An indomethacin analogue, N-(4-chlorobenzoyl)-melatonin, is a selective inhibitor of aldo-keto reductase 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase), a potential target for the treatment of hormone dependent and hormone independent malignancies.

Michael C Byrns et al.

Biochemical pharmacology, 75(2), 484-493 (2007-10-24)

Aldo-keto reductase (AKR) 1C3 (type 2 3alpha-HSD, type 5 17beta-HSD, and prostaglandin F synthase) regulates ligand access to steroid hormone and prostaglandin receptors and may stimulate proliferation of prostate and breast cancer cells. NSAIDs are known inhibitors of AKR1C enzymes.

4-Carbomethoxybenzaldehyde as a highly sensitive pre-column fluorescence derivatization reagent for 9,10-phenanthrenequinone.

Naoya Kishikawa et al.

Talanta, 85(1), 809-812 (2011-06-08)

9,10-Phenanthrenequinone (PQ) is harmful environmental pollutant that is detected in airborne particulates. The measurement of PQ in the air should be necessary to evaluate the potential adverse effects of PQ on human health. We have recently developed a determination method

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