质量水平
方案
98%
mp
144-146 °C (lit.)
官能团
carboxylic acid
hydroxyl
SMILES字符串
CC(C)C(O)(CC(O)=O)C(O)=O
InChI
1S/C7H12O5/c1-4(2)7(12,6(10)11)3-5(8)9/h4,12H,3H2,1-2H3,(H,8,9)(H,10,11)
InChI key
BITYXLXUCSKTJS-UHFFFAOYSA-N
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一般描述
2-异丙基苹果酸是亮氨酸生物合成过程中形成的中间体。芽殖酵母 酿酒酵母 分泌 2-异丙基苹果酸，并通过与AI离子形成螯合物来帮助降低铝毒性，从而阻止铝进入细胞。
应用
采用基于 GC/MS 的人血清代谢组学方法，以 2-异丙基苹果酸作为胰腺癌诊断模型的内标物。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Shaoxia Pu et al.
Poultry science, 99(9), 4586-4597 (2020-09-02)
Reproductive failure associated with heat stress is a well-known phenomenon in poultry. High temperatures also induce various metabolic disturbances in many animals. Because the liver plays a central role in metabolism, the present study aimed to clarify the relationship between
Y Hu et al.
Molecular and cellular biology, 15(1), 52-57 (1995-01-01)
The Leu3 protein of Saccharomyces cerevisiae has been shown to be a transcriptional regulator of genes encoding enzymes of the branched-chain amino acid biosynthetic pathways. Leu3 binds to upstream activating sequences (UASLEU) found in the promoters of LEU1, LEU2, LEU4
Gaelen Burke et al.
The ISME journal, 4(2), 242-252 (2009-11-13)
We examined metabolite pools of pea aphids with different facultative symbiont infections, and characterized their effects on aphid metabolism in baseline and heat stress conditions. The bacterial symbiont Serratia symbiotica protects aphid hosts from the detrimental results of heat stress
Anna Mizusawa et al.
Nutrients, 12(8) (2020-08-06)
Branched-chain amino acid (BCAA) catabolism is regulated by its rate-limiting enzyme, branched-chain α-keto acid dehydrogenase (BCKDH), which is negatively regulated by BCKDH kinase (BDK). Loss of BDK function in mice and humans leads to dysregulated BCAA catabolism accompanied by neurological
Satoshi Takemoto et al.
Animal science journal = Nihon chikusan Gakkaiho, 88(12), 1970-1978 (2017-07-20)
Long-distance transportation is sometimes inevitable in the beef industry because of the geographic separation of major breeding and fattening areas. Long-distance transportation negatively impacts production and health of cattle, which may, at least partly, result from the disturbance of metabolism
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