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关于此项目
线性分子式:
H2NCH2CH2NH(CH2)3NHCH2CH2NH2
化学文摘社编号:
分子量:
160.26
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
225-254-1
Beilstein/REAXYS Number:
1742732
MDL number:
Assay:
97%
Form:
liquid
Quality Level
assay
97%
form
liquid
refractive index
n20/D 1.494 (lit.)
bp
142-145 °C/8 mmHg (lit.)
density
0.96 g/mL at 25 °C (lit.)
functional group
amine
SMILES string
NCCNCCCNCCN
InChI
1S/C7H20N4/c8-2-6-10-4-1-5-11-7-3-9/h10-11H,1-9H2
InChI key
UWMHHZFHBCYGCV-UHFFFAOYSA-N
General description
N,N′-双(2-氨基乙基)-1,3-丙二胺是高亲和力的 Cu(II)螯合剂。它通过在人早幼粒细胞白血病细胞系(HL-60)中引起细胞铜缺乏而抑制线粒体细胞色素 C 氧化酶。
Application
N,N′-双(2-氨基乙基)-1,3-丙二胺用于研究编码铜的大肠埃希氏菌超氧化物歧化酶基因的调控。
signalword
Danger
hcodes
Hazard Classifications
Skin Corr. 1B
存储类别
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
230.0 °F - closed cup
flash_point_c
110 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Laura J Raymond et al.
Experimental biology and medicine (Maywood, N.J.), 229(9), 885-894 (2004-09-25)
Cytochrome c oxidase (CCO) is the Cu-dependent, terminal respiratory complex of the mitochondrial electron transport chain. Inhibition of CCO can promote oxidative stress by increasing mitochondrial production of reactive oxygen species (ROS). Because mitochondria have an important role in apoptosis
A S Gort et al.
Molecular microbiology, 32(1), 179-191 (1999-04-27)
The discovery of superoxide dismutase (CuZnSOD) within the periplasms of several Gram-negative pathogens suggested that this enzyme evolved to protect cells from exogenous sources of superoxide, such as the oxidative burst of phagocytes. However, its presence in some non-pathogenic bacteria
Zhouxi Wang et al.
BMC bioinformatics, 14 Suppl 3, S13-S13 (2013-03-27)
The prediction of biochemical function from the 3D structure of a protein has proved to be much more difficult than was originally foreseen. A reliable method to test the likelihood of putative annotations and to predict function from structure would
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 333131-5G | 04061836819491 |
| 333131-1G | 04061836819484 |
