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关于此项目
线性分子式:
BrC6H4CH=CHCONHC2H5
化学文摘社编号:
分子量:
254.12
UNSPSC Code:
12352100
PubChem Substance ID:
MDL number:
assay
99%
InChI
1S/C11H12BrNO/c1-2-13-11(14)7-6-9-4-3-5-10(12)8-9/h3-8H,2H2,1H3,(H,13,14)/b7-6+
SMILES string
CCNC(=O)\C=C\c1cccc(Br)c1
InChI key
LDCXGZCEMNMWIL-VOTSOKGWSA-N
mp
89-91 °C (lit.)
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
H M Corwin et al.
Epilepsia, 24(4), 427-430 (1983-08-01)
Cinromide (BW-122U) was evaluated in an open pilot study of absence seizures in three naive (previously untreated for absence seizures) patients (one male and two females, 7 to 8 years of age). In these naive patients, cinromide was found to
J W Allen et al.
Epilepsia, 24(4), 422-426 (1983-08-01)
A double-blind controlled trial of cinromide in 25 adult subjects with refractory epilepsy using the maximum tolerated dose showed that it possessed no significant antiepileptic properties.
Cinromide (3-bromo-N-ethylcinnanamide), novel anticonvulsant agent.
F E Soroko et al.
The Journal of pharmacy and pharmacology, 33(11), 741-743 (1981-11-01)
J S Lockard et al.
Epilepsia, 21(2), 177-182 (1980-04-01)
In a previous study (Lockard et al., 1979) Cinromide (3 bromo-N-ethylcinnamamide), an experimental anticonvulsant (Burroughs-Wellcome Pharmaceutical Co.), was given a preliminary evaluation. Since that research was concerned primarily with EEG paroxysms, the present study was conducted to address drug efficacy
P Chiu et al.
Neuropharmacology, 21(3), 273-276 (1982-03-01)
Cinromide, an experimental anticonvulsant (Burroughs Wellcome Co.) was tested against focal cortical (simple partial analog), focal amygdala (complex partial analog), and generalized convulsive (tonic-clonic analog) seizures in the "kindled" rat. The toxicity in the CNS was measured by the ataxia
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