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Merck
CN

374334

Sigma-Aldrich

1,1,1,2-四氟乙烷

≥99%

别名:

HFC-134a

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线性分子式:
FCH2CF3
化学文摘社编号:
分子量:
102.03
EC 号:
MDL编号:
UNSPSC代码:
12142100
PubChem化学物质编号:
NACRES:
NA.22
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方案

≥99%

沸点

−26.5 °C (lit.)

官能团

fluoro

SMILES字符串

FCC(F)(F)F

InChI

1S/C2H2F4/c3-1-2(4,5)6/h1H2

InChI key

LVGUZGTVOIAKKC-UHFFFAOYSA-N

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一般描述

1,1,1,2-Tetrafluoroethane is used as a trifluorovinylating agent in organic synthesis. It is identified as a potential refrigerant used in place of chlorofluorocarbons. 1,1,1,2-Tetrafluoroethane can also be used as a solvent and medical propellant for a wide range of applications. It is used to extract materials of natural origin like natural flavors, fragrances, and nutraceuticals.

应用

1,1,1,2-Tetrafluoroethane can be used:
  • As a solvent in the preparation of cross-linked polymer microspheres through the dispersion polymerization method.
  • As a porogenic solvent in the preparation of porous polymethacrylate monolith via free radical polymerization.
  • In the synthesis of trifluorovinyllithium, a key intermediate for the preparation of 2-halo-2,3-dideoxy-arabinose derivatives of biological importance.

包装

Supplied in a Sure/Pac cylinder and has a brass needle valve with a male 1/4" NPTF outlet thread installed. Before using the cylinder, ensure that the valve is closed, then remove the galvanized steel hex cap that seals the outlet valve.

Compatible with the following:

法律信息

Aldrich is a registered trademark of Sigma-Aldrich Co. LLC
Sure/Pac is a trademark of Sigma-Aldrich Co. LLC

象形图

Gas cylinder

警示用语:

Warning

危险声明

预防措施声明

危险分类

Press. Gas Compr. Gas

储存分类代码

2A - Gases

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Yang Chen et al.
Pharmaceutical research, 32(9), 2928-2936 (2015-03-20)
This study investigated the effect of different active pharmaceutical ingredients (API) on aerosol electrostatic charges and aerosol performances for pressurized metered dose inhalers (pMDIs), using both insulating and conducting actuators. Five solution-based pMDIs containing different API ingredients including: beclomethasone dipropionate
Daniel Moraga-Espinoza et al.
International journal of pharmaceutics, 543(1-2), 376-385 (2018-04-11)
High-speed laser imaging (HSLI) is the preferred technique to characterize the geometry of the plume in pressurized metered dose inhalers (pMDIs). However, current methods do not allow for simulation of inhalation airflow and do not use drug mass quantification to
Lena Ernstgård et al.
Journal of applied toxicology : JAT, 30(1), 59-62 (2009-08-25)
Blood-air and tissue-blood coefficients (lambda) are essential to characterize the uptake and disposition of volatile substances, e.g. by physiologically based pharmacokinetic (PBPK) modelling. Highly volatile chemicals, including many hydrofluorocarbons (HFC) have low solubility in liquid media. These characteristics pose challenges
P D Levin et al.
British journal of anaesthesia, 92(6), 865-869 (2004-05-04)
1,1,1,2 Tetrafluoroethane is a hydrofluoroalkane (HFA) that is replacing chlorofluorocarbons (CFC) as a medical aerosol propellant in an attempt to reduce damage to the ozone layer. This study compared the effects of HFA- and CFC-based inhalers on four anaesthetic gas
Synthesis of porous cross-linked polymer monoliths using 1, 1, 1, 2-tetrafluoroethane (R134a) as the porogen
Hebb AK, et al.
Composites Science and Technology, 63(16), 2379-2387 (2003)

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