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Merck
CN

374334

1,1,1,2-四氟乙烷

≥99%

别名:

HFC-134a

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关于此项目

线性分子式:
FCH2CF3
化学文摘社编号:
分子量:
102.03
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12142100
EC Number:
212-377-0
MDL number:
Assay:
≥99%
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assay

≥99%

bp

−26.5 °C (lit.)

functional group

fluoro

SMILES string

FCC(F)(F)F

InChI

1S/C2H2F4/c3-1-2(4,5)6/h1H2

InChI key

LVGUZGTVOIAKKC-UHFFFAOYSA-N

General description

1,1,1,2-Tetrafluoroethane is used as a trifluorovinylating agent in organic synthesis. It is identified as a potential refrigerant used in place of chlorofluorocarbons. 1,1,1,2-Tetrafluoroethane can also be used as a solvent and medical propellant for a wide range of applications. It is used to extract materials of natural origin like natural flavors, fragrances, and nutraceuticals.

Application

1,1,1,2-Tetrafluoroethane can be used:
  • As a solvent in the preparation of cross-linked polymer microspheres through the dispersion polymerization method.
  • As a porogenic solvent in the preparation of porous polymethacrylate monolith via free radical polymerization.
  • In the synthesis of trifluorovinyllithium, a key intermediate for the preparation of 2-halo-2,3-dideoxy-arabinose derivatives of biological importance.

Packaging

Supplied in a Sure/Pac cylinder and has a brass needle valve with a male 1/4" NPTF outlet thread installed. Before using the cylinder, ensure that the valve is closed, then remove the galvanized steel hex cap that seals the outlet valve.

Compatible with the following:

Legal Information

Aldrich is a registered trademark of Sigma-Aldrich Co. LLC
Sure/Pac is a trademark of Sigma-Aldrich Co. LLC


pictograms

Gas cylinder

signalword

Warning

hcodes

Hazard Classifications

Press. Gas Compr. Gas

存储类别

2A - Gases

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Yang Chen et al.
Pharmaceutical research, 32(9), 2928-2936 (2015-03-20)
This study investigated the effect of different active pharmaceutical ingredients (API) on aerosol electrostatic charges and aerosol performances for pressurized metered dose inhalers (pMDIs), using both insulating and conducting actuators. Five solution-based pMDIs containing different API ingredients including: beclomethasone dipropionate
Daniel Moraga-Espinoza et al.
International journal of pharmaceutics, 543(1-2), 376-385 (2018-04-11)
High-speed laser imaging (HSLI) is the preferred technique to characterize the geometry of the plume in pressurized metered dose inhalers (pMDIs). However, current methods do not allow for simulation of inhalation airflow and do not use drug mass quantification to
Lena Ernstgård et al.
Journal of applied toxicology : JAT, 30(1), 59-62 (2009-08-25)
Blood-air and tissue-blood coefficients (lambda) are essential to characterize the uptake and disposition of volatile substances, e.g. by physiologically based pharmacokinetic (PBPK) modelling. Highly volatile chemicals, including many hydrofluorocarbons (HFC) have low solubility in liquid media. These characteristics pose challenges



全球贸易项目编号

货号GTIN
374334-100G04061833021460