374334
1,1,1,2-四氟乙烷
≥99%
别名:
HFC-134a
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线性分子式:
FCH2CF3
化学文摘社编号:
分子量:
102.03
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12142100
EC Number:
212-377-0
MDL number:
Assay:
≥99%
InChI key
LVGUZGTVOIAKKC-UHFFFAOYSA-N
InChI
1S/C2H2F4/c3-1-2(4,5)6/h1H2
SMILES string
FCC(F)(F)F
assay
≥99%
bp
−26.5 °C (lit.)
functional group
fluoro
General description
1,1,1,2-Tetrafluoroethane is used as a trifluorovinylating agent in organic synthesis. It is identified as a potential refrigerant used in place of chlorofluorocarbons. 1,1,1,2-Tetrafluoroethane can also be used as a solvent and medical propellant for a wide range of applications. It is used to extract materials of natural origin like natural flavors, fragrances, and nutraceuticals.
Application
1,1,1,2-Tetrafluoroethane can be used:
- As a solvent in the preparation of cross-linked polymer microspheres through the dispersion polymerization method.
- As a porogenic solvent in the preparation of porous polymethacrylate monolith via free radical polymerization.
- In the synthesis of trifluorovinyllithium, a key intermediate for the preparation of 2-halo-2,3-dideoxy-arabinose derivatives of biological importance.
Packaging
Supplied in a Sure/Pac™ cylinder and has a brass needle valve with a male 1/4" NPTF outlet thread installed. Before using the cylinder, ensure that the valve is closed, then remove the galvanized steel hex cap that seals the outlet valve.
Compatible with the following:
Compatible with the following:
Legal Information
Aldrich is a registered trademark of Sigma-Aldrich Co. LLC
Sure/Pac is a trademark of Sigma-Aldrich Co. LLC
signalword
Warning
hcodes
pcodes
Hazard Classifications
Press. Gas Compr. Gas
存储类别
2A - Gases
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Yang Chen et al.
Pharmaceutical research, 32(9), 2928-2936 (2015-03-20)
This study investigated the effect of different active pharmaceutical ingredients (API) on aerosol electrostatic charges and aerosol performances for pressurized metered dose inhalers (pMDIs), using both insulating and conducting actuators. Five solution-based pMDIs containing different API ingredients including: beclomethasone dipropionate
Lena Ernstgård et al.
Journal of applied toxicology : JAT, 30(1), 59-62 (2009-08-25)
Blood-air and tissue-blood coefficients (lambda) are essential to characterize the uptake and disposition of volatile substances, e.g. by physiologically based pharmacokinetic (PBPK) modelling. Highly volatile chemicals, including many hydrofluorocarbons (HFC) have low solubility in liquid media. These characteristics pose challenges
Daniel Moraga-Espinoza et al.
International journal of pharmaceutics, 543(1-2), 376-385 (2018-04-11)
High-speed laser imaging (HSLI) is the preferred technique to characterize the geometry of the plume in pressurized metered dose inhalers (pMDIs). However, current methods do not allow for simulation of inhalation airflow and do not use drug mass quantification to
P D Levin et al.
British journal of anaesthesia, 92(6), 865-869 (2004-05-04)
1,1,1,2 Tetrafluoroethane is a hydrofluoroalkane (HFA) that is replacing chlorofluorocarbons (CFC) as a medical aerosol propellant in an attempt to reduce damage to the ozone layer. This study compared the effects of HFA- and CFC-based inhalers on four anaesthetic gas
Stella Papasavva et al.
Environmental science & technology, 43(24), 9252-9259 (2009-12-17)
In response to recent regulations and concern over climate change, the global automotive community is evaluating alternatives to the current refrigerant used in automobile air conditioning units, 1,1,1,2-tetrafluoroethane, HFC-134a. One potential alternative is 2,3,3,3-tetrafluoropropene (HFC-1234yf, also known as HFO-1234yf). We
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