404888
1-甲基-2-苯基吲哚
99%
别名:
NSC 63793
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关于此项目
经验公式（希尔记法）:
C15H13N
化学文摘社编号:
分子量:
207.27
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
222-618-1
MDL number:
Assay:
99%
InChI key
SFWZZSXCWQTORH-UHFFFAOYSA-N
InChI
1S/C15H13N/c1-16-14-10-6-5-9-13(14)11-15(16)12-7-3-2-4-8-12/h2-11H,1H3
SMILES string
Cn1c(cc2ccccc12)-c3ccccc3
assay
99%
mp
98-100 °C (lit.)
functional group
phenyl
Quality Level
General description
Reaction of 1-methyl-2-phenylindole with nitrogen dioxide or with nitrous acid (NaNO2-CH3COOH) in benzene has been studied. 1-Methyl-2-phenylindole is reported to react with malondialdehyde (MDA) and 4-hydroxyalkenals to afford a stable chromophore with intense maximal absorbance at 586nm.
Application
1-Methyl-2-phenylindole may be used in the following studies:
- The estimation of lipid peroxidation in third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ)Bg.
- As chromogenic agent for the determination of estimation of malondialdehyde (MDA) production.
- Colorimetric assay of lipid peroxidation.
- Synthesis of 1-methyl-2-phenyl-3-(1,3,4-thiadiazol-2-yldiazenyl)-1H-indole.
- Synthesis of 3-(5-ethyl-1,3,4-thiadiazol-2-yldiazenyl)-1-methyl-2-phenyl-1H-indole.
Reactant for preparation of:
Reactant for:
- Cyano indoles
- Difluorohydroxy indoles
Reactant for:
- Carboxylation of indoles
- Allylation of indoles
- Formylation of indoles
- Nitrosylation of indoles
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
1-Methyl-2-phenyl-3-(1, 3, 4-thiadiazol-2-yldiazenyl)-1H-indole.
Seferoglu Z, et al.
Acta Crystallographica Section E, Structure Reports Online, 63(1), 148-150 (2007)
Jan Bilski et al.
Nutrients, 11(5) (2019-05-24)
Inflammatory bowel diseases are a heterogeneous group of disorders represented by two major phenotypic forms, Crohn's disease and ulcerative colitis. Cross talk between adipokines and myokines, as well as changes in intestinal microcirculation, was proposed in pathogenesis of these disorders.
M Olleros Santos-Ruiz et al.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 35, 21-32 (2017-06-27)
We previously described in cirrhosis and aging, both conditions of IGF-1 deficiency, a clear hepatic mitochondrial dysfunction with increased oxidative damage. In both conditions, the hepatic mitochondrial function was improved with low doses of IGF-1. The aim of this work
Renato Dantas-Medeiros et al.
Journal of ethnopharmacology, 264, 113229-113229 (2020-08-19)
Commiphora leptophloeos (Mart.) J.B. Gillett (Burseraceae) is a medicinal plant native from the brazilian northeast caatinga biome, known popularly as "imburana" or "imburana-de-cambão". The leaves of C. leptophloeos are widely used in folk medicine in the treatment of various inflammatory
Yasir Hasan Siddique et al.
Pharmaceutical methods, 3(2), 94-97 (2013-06-20)
A method using 1-methyl-2-phenylindole was developed for the estimation of lipid peroxidation in third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ)Bg (9). The method is specific for the estimation of malonaldehyde. The larvae were exposed to 0.0025, 0.025, 0.050, and
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