assay
98%
form
liquid
refractive index
n20/D 1.53 (lit.)
bp
95 °C/50 mmHg (lit.)
density
1.494 g/mL at 25 °C (lit.)
SMILES string
Cc1ccc(Br)c(F)c1
InChI
1S/C7H6BrF/c1-5-2-3-6(8)7(9)4-5/h2-4H,1H3
InChI key
SLFNGVGRINFJLK-UHFFFAOYSA-N
General description
4-Bromo-3-fluorotoluene (1-bromo-2-fluoro-4-methylbenzene) is an aryl fluorinated building block. Synthesis of 4-bromo-3-fluorotoluene from o-nitro-p-toluidine (Fast Red Base GL), via diazo reaction at high temperature, Sandmeyer reaction, reduction and Schiemann reaction has been reported. Its density and refractive index have been determined.
Application
4-Bromo-3-fluorotoluene may be used in the preparation of 1-(4-cyano-3- fluorobenzyl)-5-imidazolecarboxaldehyde and 1-bromo-4-bromomethyl-2-fluorobenzene.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
95.0 °F - closed cup
flash_point_c
35 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
J M Bergman et al.
Bioorganic & medicinal chemistry letters, 11(11), 1411-1415 (2001-05-30)
A series of aryloxy substituted piperazinones with dual farnesyltransferase/geranylgeranyltransferase-I inhibitory activity was prepared. These compounds were found to have potent inhibitory activity in vitro and are promising agents for the inhibition of Ki-Ras signaling.
SYNTHESIS OF 4-CHLORO-3-FLUOROTOLUENE AND 4-BROMO-3-FLUOROTOLUENE [J].
Tao ZHXXJ.
Speciality Petrochemicals, 1, 014-014 (2007)
Yaws CL.
The Yaws Handbook of Physical Properties for Hydrocarbons and Chemicals, 91-91 (2015)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 407089-5G | 04061837073427 |