assay
98%
refractive index
n20/D 1.587 (lit.)
bp
277 °C (lit.)
density
1.158 g/mL at 25 °C (lit.)
SMILES string
C1CN(CCN1)c2ncccn2
InChI
1S/C8H12N4/c1-2-10-8(11-3-1)12-6-4-9-5-7-12/h1-3,9H,4-7H2
InChI key
MRBFGEHILMYPTF-UHFFFAOYSA-N
General description
1-(2-嘧啶基)哌嗪是一种基于哌嗪的衍生物。它是丁螺环酮的代谢产物。
Application
1-(2-嘧啶基)哌嗪可用于以下研究:
- 作为多肽羧基的衍生试剂。
- 磷酸肽分光光度分析过程中的羧基衍生化。
- 用于合成 3-{{(4-(嘧啶-2-基)哌嗪-1-基)甲基 }-1 H -吡咯并 [2,3- b ] 吡啶的起始试剂。
- 3-苯基-6-(4-(嘧啶-2-基)哌嗪-1-基)哒嗪-4-醇的合成。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
>230.0 °F
flash_point_c
> 110 °C
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
M Hascoët et al.
Pharmacology, biochemistry, and behavior, 67(1), 45-53 (2000-12-13)
Although numerous animal procedures have been employed in the study of antidepressants (ADs) in anxiety, the results following acute administration remain highly variable. The present study investigated the effect of the SSRI paroxetine (4, 8, and 16 mg/kg, IP) in
Xiaoqiang Qiao et al.
Rapid communications in mass spectrometry : RCM, 25(5), 639-646 (2011-02-04)
Piperazine-based derivatives, including 1-(2-pyridyl)piperazine (2-PP), 1-(2-pyrimidyl)piperazine (2-PMP), 1-(4-pyridyl)piperazine (4-PP), and 1-(1-methyl-4-piperidinyl)piperazine (M-PP), were used for the derivatization of carboxyl groups on peptides with 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDC) and 1-hydroxy-7-azabenzotriazole (HOAt) as coupling reagents, and trifluoroacetic acid (TFA) as activator. Taking synthetic
K T Kivistö et al.
Pharmacology & toxicology, 84(2), 94-97 (1999-03-06)
The effects of inhibition and induction of the metabolism of buspirone on the plasma concentrations of 1-(2-pyrimidinyl)-piperazine (a piperazine metabolite), the principal active metabolite of buspirone, were investigated. Two separate randomized, placebo-controlled cross-over studies with two phases were carried out
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 421235-25G | 04061833389775 |
| 421235-5G | 04061832093734 |
