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Merck
CN

466387

Sigma-Aldrich

Brij® S 100

average Mn ~4,670

别名:

聚氧乙烯(100)十八烷基醚

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关于此项目

线性分子式:
C18H37(OCH2CH2)nOH, n~100
CAS Number:
MDL编号:
UNSPSC代码:
12162002
PubChem化学物质编号:
NACRES:
NA.23
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分子量

average Mn ~4,670

质量水平

mp

51-54 °C (lit.)

羟基值

13‑25 mg KOH/g

溶解性

propylene glycol and xylene: insoluble

密度

1.1 g/mL at 25 °C (lit.)

HLB

18

SMILES字符串

O(CC[O])CCCCCCCCCCCCCCCCCC

InChI

1S/C20H41O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h2-20H2,1H3

InChI key

PSEGVHKUPXNGGJ-UHFFFAOYSA-N

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应用

Brij® S 100 可用于:
  • 作为一种非离子表面活性剂研究其与鲁米诺的相互作用电化学发光用于生物分析
  • 作为载体材料,利用气体饱和溶液(PGSS)工艺中的颗粒研究尼莫地平、非诺贝特和 香草醛的配方
  • 作为浇铸溶液中的亲水性表面活性剂,制备不对称平板纳滤膜,并研究其对聚醚砜(PES)纳滤膜亲水性能的影响

法律信息

Brij is a registered trademark of Croda International PLC

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Formulation of nimodipine, fenofibrate, and o-vanillin with Brij S100 and PEG 4000 using the PGSS process
Kravanja G, et al.
Journal of Supercritical Fluids, 135, 245-253 (2018)
J Q Zhang et al.
Drug delivery, 14(6), 381-387 (2007-08-19)
The study describes the development of stealth solid lipid nanoparticles (SLNs) as colloidal carriers for silibinin, a drug with very low solubility. Stealth SLNs were constituted mainly of bioacceptable and biodegradable lipids, such as stearic acid and surfactant Brij 78
S O Williams et al.
Drug development and industrial pharmacy, 26(1), 71-77 (2000-04-01)
The purpose of this study was to scale up an oil/water (o/w) cream formulation containing 40% diethylene glycol monoethyl ether (DGME), developed via 300-g laboratory batches in a 2(5-2) fractional factorial design, to 7-kg batch sizes in a Brogli-10 homogenizer.
Jae-Haeng Song et al.
Drug development and industrial pharmacy, 35(8), 897-903 (2009-02-26)
The oral administration of loratadine, an antihistamine, can have a variety of adverse side effects, such as headache, fatigue, and nausea, because of the transient high blood concentration. To avoid these effects, loratadine can be administered using a transdermal drug
Anne Huhtala et al.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 19(1), 11-21 (2003-03-22)
This study was undertaken to investigate the use of the in vitro test WST-1, an assay of cell proliferation and viability, for a preliminary safety evaluation of topical ophthalmic preparations. The cytotoxicity of two surfactants, benzalkonium chloride (BAC) and polyoxyethylene-20-stearyl

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