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472565

氰基膦酸二乙酯

Name: 氰基膦酸二乙酯
Brand: ALDRICH

90%

别名:

DEPC, 氰代磷酸二乙酯

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关于此项目

线性分子式:

(CH₃CH₂O)₂P(O)CN

化学文摘社编号:

2942-58-7

分子量:

163.11

EC Number:

220-936-5

UNSPSC Code:

12352100

PubChem Substance ID:

24870809

Beilstein/REAXYS Number:

1768938

MDL number:

MFCD00010256

Assay:

90%

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属性

assay

90%

refractive index

n20/D 1.403 (lit.)

bp

104-105 °C/19 mmHg (lit.)

density

1.075 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CCOP(=O)(OCC)C#N

InChI

1S/C5H10NO3P/c1-3-8-10(7,5-6)9-4-2/h3-4H2,1-2H3

InChI key

ZWWWLCMDTZFSOO-UHFFFAOYSA-N

说明

General description

氰基膦酸二乙酯（DCNP，一种塔崩模拟物， DECP）是一种神经毒剂模拟物。使用荧光素（一种可逆荧光传感剂）对其进行检测已有报道。它在合适的有机催化剂（不同的胺、氨基醇和二醇）存在下的降解已有研究。

Application

肽合成的偶联剂。苯酚的磷酸化试剂。羧酸荧光衍生化的活化剂，可通过 HPLC 分离活化剂。

Other Notes

含磷酸三乙酯

pictograms

GHS06,GHS05

signalword

Danger

hcodes

H300 + H310 + H330,H314

pcodes

P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1B

supp_hazards

EUH032

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

176.0 °F - closed cup

flash_point_c

80 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

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Rational design of substituted tripyrrole peptides that complex with DNA by both selective minor-groove binding and electrostatic interaction with the phosphate backbone.

T C Bruice et al.

Proceedings of the National Academy of Sciences of the United States of America, 89(5), 1700-1704 (1992-03-01)

The structures of the compounds we call 3a, 3b, and 3c-compounds that incorporate (i) the tripyrrole peptide of the minor-groove-binding distamycin class of compounds and (ii) polyamine ligands that extend from the minor groove and can interact with phosphodiester bonds--were

Anti-inflammatory effect of up-regulated microRNA-221-3p on coronary heart disease via suppressing NLRP3/ASC/pro-caspase-1 inflammasome pathway activation.

Jingfeng Rong et al.

Cell cycle (Georgetown, Tex.), 19(12), 1478-1491 (2020-05-07)

As some evidence has demonstrated the role of microRNA-221 (miR-221) on coronary heart disease (CHD), the aim of the present study was to investigate the effect of miR-221-3p on CHD via regulating NLRP3/ASC/pro-caspase-1 inflammasome pathway. Sixty CHD patients and 60

Synthetic Communications, 27, 3035-3035 (1997)

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全球贸易项目编号

货号	GTIN
472565-100ML-A	04061837657719