47587
N-芴甲氧羰基-beta-丙氨酸
≥99.0% (HPLC)
别名:
Fmoc-β-丙氨酸
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关于此项目
经验公式（希尔记法）:
C18H17NO4
化学文摘社编号:
分子量:
311.33
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
2302327
产品名称
N-芴甲氧羰基-beta-丙氨酸, ≥99.0% (HPLC)
InChI
1S/C18H17NO4/c20-17(21)9-10-19-18(22)23-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2,(H,19,22)(H,20,21)
SMILES string
OC(=O)CCNC(=O)OCC1c2ccccc2-c3ccccc13
InChI key
LINBWYYLPWJQHE-UHFFFAOYSA-N
assay
≥99.0% (HPLC)
form
powder or crystals
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
mp
142-147 °C
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
2-8°C
Quality Level
Application
Fmoc-β-Ala-OH 可用作连接子，用于通过Fmoc 固相肽合成反应在整体GMA-EDMA（甲基丙烯酸缩水甘油酯-co-乙二醇二甲基丙烯酸酯）基质上合成肽。
General description
Fmoc-β-Ala-OH也称Fmoc-β-丙氨酸，它是一种用于固相肽合成的多功能试剂。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Solid phase peptide synthesis on epoxy-bearing methacrylate monoliths
E Vlakh
Journal of Peptide Science, 10, 719-730 (2004)
Sofie Trier et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 96, 329-337 (2015-09-09)
Acylation of peptide drugs with fatty acid chains has proven beneficial for prolonging systemic circulation, as well as increasing enzymatic stability and interactions with lipid cell membranes. Thus, acylation offers several potential benefits for oral delivery of therapeutic peptides, and
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