652369
1-氨基-1-环丁烷羧酸
97%
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线性分子式:
H2NC4H6CO2H
化学文摘社编号:
分子量:
115.13
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
产品名称
1-氨基-1-环丁烷羧酸, 97%
InChI
1S/C5H9NO2/c6-5(4(7)8)2-1-3-5/h1-3,6H2,(H,7,8)
SMILES string
NC1(CCC1)C(O)=O
InChI key
FVTVMQPGKVHSEY-UHFFFAOYSA-N
assay
97%
form
solid
reaction suitability
reaction type: solution phase peptide synthesis
mp
261 °C (dec.) (lit.)
application(s)
peptide synthesis
Quality Level
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
R H Porter et al.
European journal of pharmacology, 227(1), 83-88 (1992-09-01)
The competitive N-methyl-D-aspartate (NMDA) receptor antagonist [3H]3-((+-)-2-carboxypiperazin-4-yl)propyl-1-phosphonic acid ([3H]CPP) interacts with two discrete binding sites, one of high- and the other of low-affinity, on rat forebrain synaptic plasma membranes. The high affinity site exhibited a Kd of 101.5 nM and
K F Hübner et al.
Clinical nuclear medicine, 6(6), 249-252 (1981-06-01)
Eight patients with proven or suspected neoplastic lesions were examined with 1-aminocyclobutane C-11-carboxylic acid and 1-aminocyclopentane C-11-carboxylic acid using positron emission computed tomography. The results of this comparative study have shown that both of these unnatural amino acids have a
M Gatos et al.
Journal of peptide science : an official publication of the European Peptide Society, 3(2), 110-122 (1997-03-01)
A series of N- and C-protected, monodispersed homo-oligopeptides (to the dodecamer level) from the small-ring alicyclic C alpha, alpha-dialkylated glycine 1-aminocyclobutane-1-carboxylic acid (Ac4c) and two Ala/Ac4c tripeptides were synthesized by solution methods and fully characterized. The conformational preferences of all
Insulin-induced phospho-oligosaccharide stimulates amino acid transport in isolated rat hepatocytes.
I Varela et al.
The Biochemical journal, 267(2), 541-544 (1990-04-15)
The ability of the insulin-induced phospho-oligosaccharide to stimulate amino acid transport was studied in isolated rat hepatocytes. At low alpha-aminoisobutyric acid concentrations (0.1 mM), both 100 nM-insulin and 10 microM-phospho-oligosaccharide doubled amino acid uptake after 2 h of incubation. This
T S Rao et al.
Neuropharmacology, 29(3), 305-309 (1990-03-01)
Following intravenous administration, 1-aminocyclobutane-1-carboxylate (ACBC, 100 mg/kg), a N-methyl-D-aspartate (NMDA)-associated glycine receptor antagonist, was eliminated with a T1/2 of 5 min in mouse brain and 4 min in rat cerebrospinal fluid (CSF). 1-Aminocyclopropane-1-carboxylate (ACC), a NMDA-associated glycine receptor agonist, was
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