主要文件

查看所有文档

690600

N-[3,5-双(三氟甲基)苯基]-N′-[(9R)-6′-甲氧基-9-金鸡宁]硫脲

Name: N-[3,5-双(三氟甲基)苯基]-N′-[(9R)-6′-甲氧基-9-金鸡宁]硫脲
Brand: ALDRICH

≥90.0%

别名:

1-[3,5-双(三氟甲基)苯基)-3-{(R)(6-甲氧基-4-喹啉基)-[(2R,4S,5R)-5-乙烯基-1-氮杂-二环[2.2.2]辛-2-基]甲基}硫脲, epi-N-奎宁基-N′-双(3,5-三氟甲基)苯硫脲

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₂₉H₂₈F₆N₄OS

化学文摘社编号:

852913-25-8

分子量:

594.61

UNSPSC Code:

12352005

PubChem Substance ID:

329761352

MDL number:

MFCD16621389

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

assay

≥90.0% (HPLC), ≥90.0%

form

lumps

functional group

amine, fluoro, thiourea

SMILES string

COc1ccc2nccc([C@@H](NC(=S)Nc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C4CC5CCN4C[C@@H]5C=C)c2c1

InChI

1S/C29H28F6N4OS/c1-3-16-15-39-9-7-17(16)10-25(39)26(22-6-8-36-24-5-4-21(40-2)14-23(22)24)38-27(41)37-20-12-18(28(30,31)32)11-19(13-20)29(33,34)35/h3-6,8,11-14,16-17,25-26H,1,7,9-10,15H2,2H3,(H2,37,38,41)/t16-,17-,25+,26+/m0/s1

InChI key

IQMKPBFOEWWDIQ-ZRJNXXGPSA-N

说明

General description

The product is a cinchona-alkaloid-derived, bifunctional catalyst containing a thiourea group at position 9.

Application

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxy-9-cinchonanyl]thiourea may be used to catalyze the formation of optically active Mannich adducts from stable N-carbamate amido sulfones via enantioselective Mannich reaction.

采用双官能金鸡纳有机催化剂，进行硝基甲烷的高度对映选择性共轭加成反应，生成查耳酮

Features and Benefits

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxy-9-cinchonanyl]thiourea as an organocatalyst has the following advantages over transition-metal catalysis:

Lower toxicity
Lower costs
Air and moisture stability for simple reaction setup

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

GHS06

signalword

Danger

hcodes

H301

pcodes

P301 + P310

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

新产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

The growing role of organocatalysis in asymmetric synthesis.

Aldrichimica Acta, 44(1), 16-16 (2011)

Asymmetric Mannich reactions with in situ generation of carbamate-protected imines by an organic catalyst.

Song J, et al.

Organic Letters, 9(4), 603-606 (2007)

Urea- and thiourea-substituted cinchona alkaloid derivatives as highly efficient bifunctional organocatalysts for the asymmetric addition of malonate to nitroalkenes: inversion of configuration at C9 dramatically improves catalyst performance.

Séamus H McCooey et al.

Angewandte Chemie (International ed. in English), 44(39), 6367-6370 (2005-09-02)

查看所有相关文献

全球贸易项目编号

货号	GTIN
690600-250MG	04061832624525