857661
4-氨基联苯胺 二盐酸盐
98%
别名:
p-氨基苯甲酰胺二盐酸盐
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关于此项目
线性分子式:
H2NC6H4C(=NH)NH2·2HCl
化学文摘社编号:
分子量:
208.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
219-692-2
Beilstein/REAXYS Number:
3692927
MDL number:
产品名称
4-氨基联苯胺 二盐酸盐, 98%
InChI key
GHEHNICLPWTXJC-UHFFFAOYSA-N
InChI
1S/C7H9N3.2ClH/c8-6-3-1-5(2-4-6)7(9)10;;/h1-4H,8H2,(H3,9,10);2*1H
SMILES string
Cl[H].Cl[H].NC(=N)c1ccc(N)cc1
assay
98%
form
crystals
mp
>300 °C (lit.)
functional group
amine
storage temp.
2-8°C
Quality Level
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Application
4-二盐酸氨基苯甲脒可用于合成：
- 基于苯甲脒的口服活性纤维蛋白原受体拮抗剂。
- 苯甲脒衍生物，其是选择性和有效的丝氨酸蛋白酶抑制剂。
- 新型吡咯并[3,2-c]喹啉，其是拓扑异构酶抑制剂（例如甲氧檗因和法格罗宁）的结构类似物。
4-二盐酸氨基苯甲脒在亲和层析中可用作配体，用于酶的纯化和固定。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Reactive polymers have been prepared by copolymeriz-ing N-isopropyl acrylamide (NIPAM) with N-acryloxy-succinimide (NASI) or glycidyl methacrylate (GMA). The amino groups of ligands could react with the residues of NASI or GMA and the polymers could be precipitated by temperature and/or
A synthesis of new pyrrolo [3, 2?c] quinolines.
Dudouit F, et al.
Journal of Heterocyclic Chemistry, 38(3), 755-758 (2001)
A L Nguyen et al.
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A reactive water-soluble polymer was synthesized by copolymerizing N-isopropylacrylamide and glycidyl acrylate. The reactive polymer could react with the amino groups of enzymes/proteins or other ligands to form an affinity polymer. As a model, the reactive polymer was allowed to
Specific adsorption of serine proteases on coated silica beads substituted with amidine derivatives.
S Khamlichi et al.
Journal of chromatography, 510, 123-132 (1990-06-27)
Amidine derivatives interact with serine proteases, the inhibition being due to interactions between amidine functions and the active sites of the enzymes. Five different types of amidine (substituted or unsubstituted) were coupled to coated silica beads, which had previously been
Biochemical and molecular modeling analysis of the ability of two p-aminobenzamidine-based sorbents to selectively purify serine proteases (fibrinogenases) from snake venoms.
De-Simone S G, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 822(1-2), 1-9 (2005)
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