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Merck
CN

901185

3,3′-Diethoxypropyl methacrylate

≥98.0%, contains ≤100 ppm MEHQ as inhibitor

别名:

3,3-Diethoxypropyl 2-methylprop-2-enoate, DEPMA, Diethoxypropyl methacrylate

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关于此项目

经验公式(希尔记法):
C11H20O4
化学文摘社编号:
分子量:
216.27
NACRES:
NA.23
UNSPSC Code:
12162002
MDL number:
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产品名称

3,3′-Diethoxypropyl methacrylate, ≥98.0%, contains ≤100 ppm MEHQ as inhibitor

InChI

1S/C11H20O4/c1-5-13-10(14-6-2)7-8-15-11(12)9(3)4/h10H,3,5-8H2,1-2,4H3

InChI key

CPARKAXEDHCHNX-UHFFFAOYSA-N

assay

≥98.0%

form

liquid

contains

≤100 ppm MEHQ as inhibitor

color

colorless to pale yellow

shipped in

wet ice

storage temp.

−20°C

Application

3,3′-Diethoxypropyl methacrylate is a methacrylate monomer used in the synthesis of the pH-responsive polymer poly(3,3′-diethoxypropyl methacrylate) (PDEPMA). PDEPMA contains acetal groups, which upon exposure to acid in solution hydrolyze to form aldehyde groups that can be further reacted via chemical conjugation with biomolecules or other small molecules. Due to their responsive nature and well-controlled deprotection reactions, these materials have been used in a wide variety of biomedical applications such as surface patterning for sensors, the synthesis of polymer-biomolecule conjugates, and drug delivery applications.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

161.6 °F

flash_point_c

72 °C

法规信息

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分析证书(COA)

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Jungyeon Hwang et al.
Journal of controlled release : official journal of the Controlled Release Society, 122(3), 279-286 (2007-06-30)
Polymers with reactive side chains and narrow molecular weight distributions were synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization, and the potential to utilize these polymers to prepare drug carriers was demonstrated. p-Nitrophenyl methacrylate (NPMA) and diethoxypropyl methacrylate (DEPMA) were
Anja S Goldmann et al.
Macromolecular rapid communications, 34(10), 810-849 (2013-04-30)
The establishment of advanced living/controlled polymerization protocols allows for engineering synthetic polymers in a precise fashion. Combining advanced living/controlled polymerization techniques with highly efficient coupling chemistries facilitates quantitative, modular, and orthogonal functionalization of synthetic polymer strands at their chain termini
The emergence of oxime click chemistry and its utility in polymer science.
Collins J, et al.
Polym. Chem., 7, 3812-3826 (2016)
Karen L Christman et al.
Langmuir : the ACS journal of surfaces and colloids, 21(18), 8389-8393 (2005-08-24)
Protein and peptide microarrays are popular candidates for medical diagnostics because of the possibility for high sensitivity and simultaneous marker screening. To realize the potential of these arrays, new strategies for ligand patterning are needed. We report a method for

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