description
Degree of substitution: >80% by TNBS method, NMR: Conforms to structure
form
powder
color
white to pale yellow
storage temp.
2-8°C
General description
Due to its biodegradablity and biocompatibility, gelatin is routinely used in hydrogels for biomedical applications such as drug delivery, tissue engineering, and 3D bioprinting. Gelatin-based hydrogels are synthesized by the crosslinking of functionalized gelatins. Depending on the identity of the functional groups, several different processes can be used to synthesize crosslinked gelatin hydrogels, including radical-based (either thermal or photochemical) and click chemistry methods. Alkyne-functionalized gelatin can be used in the synthesis of hydrogel using click chemistry with either azide or thiol substrates.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels.
Yue K, et al.
Biomaterials, 73, 254-271 (2015)
Thiol-yne ′click′/coupling chemistry and recent applications in polymer and materials synthesis and modification.
Lowe AB, et al.
Polymer, 55, 5517-5549 (2014)
Sandeep T Koshy et al.
Advanced healthcare materials, 5(5), 541-547 (2016-01-26)
Injectable gelatin hydrogels formed with bioorthogonal click chemistry (ClickGel) are cell-responsive ECM mimics for in vitro and in vivo biomaterials applications. Gelatin polymers with pendant norbornene (GelN) or tetrazine (GelT) groups can quickly and spontaneously crosslink upon mixing, allowing for
Gelatin hydrogels via thiol-ene chemistry.
Russo L, et al.
Monatshefte fur Chemie / Chemical Monthly, 147, 587-592 (2016)
Masato Tamura et al.
Scientific reports, 5, 15060-15060 (2015-10-10)
This paper describes the generation of "click-crosslinkable" and "photodegaradable" gelatin hydrogels from the reaction between dibenzocycloctyl-terminated photoclevable tetra-arm polyethylene glycol and azide-modified gelatin. The hydrogels were formed in 30 min through the click-crosslinking reaction. The micropatterned features in the hydrogels were
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