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Merck
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主要文件

925217

Sigma-Aldrich

TissueFab® - low endotoxin GelMA-UV bioink

0.2 μm filtered, suitable for 3D bioprinting applications

别名:

Bioink, GelMA, Gelatin methacrylamide, Gelatin methacrylate, Gelatin methacryloyl

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About This Item

UNSPSC代码:
12352201
NACRES:
NA.23

质量水平

无菌性

0.2 μm filtered

表单

viscous liquid (to gel)

尺寸

10 mL

杂质

≤5 CFU/g

Bioburden

(Fungal)
≤5 CFU/g Bioburden (Aerobic)
≤50 EU/mL Endotoxin

颜色

pale yellow to colorless

pH值(酸碱度)

6.5-7.5

粘度

2-20 cP

应用

3D bioprinting

储存温度

2-8°C

一般描述

Gelatin methacryloyl (GelMA) is a polymerizable hydrogel material derived from natural extracellular matrix (ECM) components. Due to its low cost, abundance, and retention of natural cell binding motifs, gelatin has become a highly sought material for tissue engineering applications.

The addition of photocrosslinkable methacrylamide functional groups in GelMA allows the synthesis of biocompatible, biodegradable, and non-immunogenic hydrogels that are stable in biologically relevant conditions and promote cell adhesion, spreading, and proliferation.

Temporal and spatial control of the crosslinking reaction can be obtained by adjusting the degree of functionalization and polymerization conditions, allowing for the fabrication of hydrogels with unique patterns, 3D structures, and morphologies.

应用

Gelatin methacrylate based bioinks have been used in the following bioprinting applications:

  • osteogenic,
  • chondrogenic ,
  • hepatic ,
  • adipogenic ,
  • vasculogenic ,
  • epithelial ,
  • endothelial ,
  • cardiac valve ,
  • skin ,
  • tumors

特点和优势

  • Ready-to-use formulation optimized for high printing fidelity and cell viability, eliminating the lengthy bioink formulation development process
  • Step-by-step protocols developed and tested by MilliporeSigma 3D Bioprinting Scientists, no prior 3D bioprinting experience neede
  • Suitable for different extrusion-based 3D bioprinter model
  • Methacrylamide functional group can also be used to control the hydrogel physical parameters such as pore size, degradation rate, and swell ratio.

法律信息

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

WGK

WGK 3


历史批次信息供参考:

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