产品名称
Oligo(poly(ethylene glycol) fumarate), average Mn 4,500
form
viscous liquid (to powder)
mol wt
average Mn 4,500
color
white
storage temp.
−20°C
Quality Level
Features and Benefits
- Biodegradable and cytocompatible
- Crosslinkable
- Tunable mechanical properties
Application
- Biomedical applications
- Drug delivery
- Tissue engineering
- 3D bioprinting
General description
Oligo(poly(ethylene glycol) fumarate) (OPF) is a derivative of poly(ethylene glycol) (PEG). The unsaturated fumarate groups render it crosslinkable and biodegradable, with tunable mechanical properties. The multiple double bonds along the linear macromolecular chain allow for crosslinking in aqueous solutions in the presence of thermal, chemical or photochemical radical initiators.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Mahrokh Dadsetan et al.
Biomacromolecules, 8(5), 1702-1709 (2007-04-11)
Photo-cross-linkable oligo[poly(ethylene glycol) fumarate] (OPF) hydrogels have been developed for use in tissue engineering applications. We demonstrated that compressive modulus of these hydrogels increased with increasing polymer concentration, and hydrogels with different mechanical properties were formed by altering the ratio
Heungsoo Shin et al.
Biomacromolecules, 4(3), 552-560 (2003-05-14)
Currently, oligo[poly(ethylene glycol) fumarate] (OPF) hydrogels are being investigated as an injectable and biodegradable system for tissue engineering applications. In this study, cytotoxicity of each component of the OPF hydrogel formulation and the resulting cross-linked network was examined. Specifically, OPF
In vitro release of transforming growth factor-?1 from gelatin microparticles encapsulated in biodegradable, injectable oligo(poly(ethylene glycol) fumarate) hydrogels
Hollanda, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 91, 299-313 (2003)
Theresa A Holland et al.
Journal of controlled release : official journal of the Controlled Release Society, 101(1-3), 111-125 (2004-12-14)
This work describes the development of a non-invasive means of simultaneously delivering insulin-like growth factor-1 (IGF-1) and transforming growth factor-beta1 (TGF-beta1) to injured cartilage tissue in a controlled manner. This novel delivery technology employs the water-soluble polymer, oligo(poly(ethylene glycol) fumarate)
Xifeng Liu et al.
Journal of biomedical materials research. Part A, 109(1), 6-17 (2020-05-18)
3D bioprinting is a promising new tissue restoration technique that enables the precise deposition of cells and growth factors in order to more closely mimic the structure and function of native organs. In this study, we report the development of
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持