质量水平
表单
solid
颜色
off-white
粘度
10-30 Pa.s
mp
40-60 °C
凝胶强度
(Young′s modulus after UV crosslinking (Mpa) 150-200)
一般描述
The polyester-based biodegradable bioink is a photocrosslinkable, hydrophobic, and biocompatible bioink that combines the benefits of conventional stiff polyester materials with low temperature (<65°C) processability. This bioink has been used to generate and sustain 3D cellular structures of a variety of human tissues including cartilage (chondrocytes), blood vessels (HUVECs), smooh muscle cells (SMCs), and skin (HFFs).
Properties and Processing: The polyester-based biodegradable bioink is provided in a ready to print cartridge and is a semi-crystalline solid at room temperature with a melting emperature around 50°C and crystallization temperature of 25°C and displays Newtonian fluidic characteristics. The visocity of the bioink makes it suitable for an easy extrusion from the nozzlee during printing, resulting in a printable formulation in pneumatic 3D printers operating at pressures between 80-160 kPa. The ink is in molten state in the dispenser (~60°C), after which the printed constructs are solidified as a result of rapid cystrallization. The printed scaffold can then crosslinked via UV light.
Properties and Processing: The polyester-based biodegradable bioink is provided in a ready to print cartridge and is a semi-crystalline solid at room temperature with a melting emperature around 50°C and crystallization temperature of 25°C and displays Newtonian fluidic characteristics. The visocity of the bioink makes it suitable for an easy extrusion from the nozzlee during printing, resulting in a printable formulation in pneumatic 3D printers operating at pressures between 80-160 kPa. The ink is in molten state in the dispenser (~60°C), after which the printed constructs are solidified as a result of rapid cystrallization. The printed scaffold can then crosslinked via UV light.
应用
3D bioprinting
Tissue engineering
In vitro modeling
Tissue engineering
In vitro modeling
特点和优势
- Easy printing - The bioink can be processed at low temperatures followed by photocrosslinking, making it ideal for hybrid scaffolds
- Biocompatibility - Exceptional biocompatibility and no contact toxicity
- Biodegradable - Fully biodegradable materials allows cellular remodeling of printed matrix
- Easy handling - Delivered in a ready-to-use cartridge, ready to print after heating
- UV curable - Efficient UV-based crosslinking
- Reproducibility - Strict quality control
- Mechanical integrity - Robust yet flexible polymer suitable for stiffer tissue engineering applications
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Multiphoton Lithography as a Promising Tool for Biomedical Applications
Greant, Coralie
Advanced Functional Materials
, 33(39) (2023)
Olivier Guillaume et al.
Acta biomaterialia, 165, 72-85 (2022-03-16)
Since its inception, tissue engineering and regenerative medicine (TERM) has been relying on either scaffold-based or scaffold-free strategies. Recent reports outlined the possibility of a synergistic, convergence approach, referred to as the third TERM strategy, which could alleviate bottlenecks of
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