描述
applications: cell proliferation, cell culture, tissue engineering
表单
viscous liquid (or gel)
组成
PODS Human IGF-1, 25µg
PODS Human PDGF-BB, 25µg
PODS Human VEGF-165, 25µg
TissueFab® bioink, (Gel)MA Vis/405 nm, low endotoxin
杂质
Bioburden (Total Aerobic): <5 CFU/ml
Bioburden (fungal): < 5 CFU/mL
Endotoxin: <50 EU/ml
颜色
colorless to pale yellow
pH值（酸碱度）
6.5-7.5
相容性
(extrusion-based 3D bioprinting)
储存温度
−20°C
一般描述
Rethink your bioinks with TissueFab®
About the material:
The TissueFab(R) PODS Growth Factor Loaded Bioink Kit, vascularization, Vis/405 nm contains:
* Low endotoxin conductive bioink containing visible light photoinitiator
* Human PDGF-BB PODS
* Human VEGF-165 PODS
* Human IGF-1 PODS
Printing and crosslinking parameters:
*Suitable for extrusion-based bioprinting
*Visible light crosslinking at 405 nm wavelength
TissueFab(R) PODS Growth Factor Loaded Bioink kit, vascularization, Vis/405nm is a ready-to-use, GelMA based bioink kit which is formulated for high cell viability, printing fidelity, and is designed for extrusion-based 3D bioprinting and subsequent crosslinking with exposure to 405nm visible light. TissueFab(R) PODS Growth Factor Loaded Bioink kit, vascularization, GelMA Vis/405nm can be used with most extrusion-based bioprinters, is biodegradable and cytocompatible.
Included growth facors, PDGF-BB, VEGF-165, and IGF-1 are known to play crucial roles in promoting vasculogenesis and angiogenesis. Their inclusion with PODS (R) delivery system allows their sustained release within bioprinted constructs and retainment of 70% bioactivity after 6 months. When mixed with the bioink component, the included PODS (R) growth factors can promote angiogenesis.
More information and a step by step protocol can be found under the "More Documents" section of this page.
About the material:
The TissueFab(R) PODS Growth Factor Loaded Bioink Kit, vascularization, Vis/405 nm contains:
* Low endotoxin conductive bioink containing visible light photoinitiator
* Human PDGF-BB PODS
* Human VEGF-165 PODS
* Human IGF-1 PODS
Printing and crosslinking parameters:
*Suitable for extrusion-based bioprinting
*Visible light crosslinking at 405 nm wavelength
TissueFab(R) PODS Growth Factor Loaded Bioink kit, vascularization, Vis/405nm is a ready-to-use, GelMA based bioink kit which is formulated for high cell viability, printing fidelity, and is designed for extrusion-based 3D bioprinting and subsequent crosslinking with exposure to 405nm visible light. TissueFab(R) PODS Growth Factor Loaded Bioink kit, vascularization, GelMA Vis/405nm can be used with most extrusion-based bioprinters, is biodegradable and cytocompatible.
Included growth facors, PDGF-BB, VEGF-165, and IGF-1 are known to play crucial roles in promoting vasculogenesis and angiogenesis. Their inclusion with PODS (R) delivery system allows their sustained release within bioprinted constructs and retainment of 70% bioactivity after 6 months. When mixed with the bioink component, the included PODS (R) growth factors can promote angiogenesis.
More information and a step by step protocol can be found under the "More Documents" section of this page.
应用
TissueFab(R) PODS Growth Factor Loaded Bioink kit, vascularization, Vis/405nm enables the precise fabrication of 3D cell models and tissue constructs for research in 3D cell biology, tissue engineering, in vitro tissue models, and regenerative medicine.
特点和优势
Key Features and Benefits:
Each TissueFab(R) bioink is developed and tested to meet strict criteria to best suit researchers′ needs. This includes:
• Printability and rheological properties
• Crosslinking
• Cell viability
• Biocompatibility
• Low bioburden
• Low endotoxin
This product contains 10 ml of bioink solution and growth factors PODS packaged separately to allow for optimization.
Each TissueFab(R) bioink is developed and tested to meet strict criteria to best suit researchers′ needs. This includes:
• Printability and rheological properties
• Crosslinking
• Cell viability
• Biocompatibility
• Low bioburden
• Low endotoxin
This product contains 10 ml of bioink solution and growth factors PODS packaged separately to allow for optimization.
法律信息
TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
10 - Combustible liquids
WGK
WGK 3
法规信息
新产品
此项目有
Bioactive nanoengineered hydrogels for bone tissue engineering: a growth-factor-free approach
Xavier R, et al.
ACS Nano, 9(3), 3109-3118 (2015)
Masabumi Shibuya
Genes & cancer, 2(12), 1097-1105 (2012-08-07)
The vascular endothelial growth factor (VEGF) and its receptor (VEGFR) have been shown to play major roles not only in physiological but also in most pathological angiogenesis, such as cancer. VEGF belongs to the PDGF supergene family characterized by 8
Marius Raica et al.
Pharmaceuticals (Basel, Switzerland), 3(3), 572-599 (2010-03-11)
Angiogenesis in normal and pathological conditions is a multi-step process governed by positive and negative endogenous regulators. Many growth factors are involved in different steps of angiogenesis, like vascular endothelial growth factors (VEGF), fibroblast growth factor (FGF)-2 or platelet-derived growth
Insulin-like growth factors promote vasculogenesis in embryonic stem cells
Piecewicz M P, et al.
PLoS ONE, 7(2), 32191-32191 (2012)
Y Shi et al.
Biomedical materials (Bristol, England), 13(3), 035008-035008 (2018-01-09)
Three-dimensional bioprinting is an emerging technology for fabricating living 3D constructs, and it has shown great promise in tissue engineering. Bioinks are scaffold materials mixed with cells used by 3D bioprinting to form a required cell-laden structure. In this paper
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