A16602
DL-N-乙酰高半胱氨酸硫内酯
98%
别名:
2-乙酰胺基-4-巯基丁酸-γ-硫代内酯
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关于此项目
经验公式（希尔记法）:
C6H9NO2S
化学文摘社编号:
分子量:
159.21
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
214-793-8
MDL number:
Assay:
98%
Form:
powder
InChI
1S/C6H9NO2S/c1-4(8)7-5-2-3-10-6(5)9/h5H,2-3H2,1H3,(H,7,8)
InChI key
NRFJZTXWLKPZAV-UHFFFAOYSA-N
SMILES string
CC(=O)NC1CCSC1=O
assay
98%
form
powder
mp
109-111 °C (lit.)
Quality Level
Application
<ul>
<li><strong>稳定的油填充微胶囊的超声合成：</strong>本研究探索了使用硫醇化壳聚糖的油填充微胶囊的超声合成，可能涉及像 N-乙酰高半胱氨酸硫醇内酯这样的衍生物，以提高稳定性和功能特性。该研究提供了与制药和工业应用相关的先进微胶囊技术的见解（
<li><strong>稳定的油填充微胶囊的超声合成：</strong>本研究探索了使用硫醇化壳聚糖的油填充微胶囊的超声合成，可能涉及像 N-乙酰高半胱氨酸硫醇内酯这样的衍生物，以提高稳定性和功能特性。该研究提供了与制药和工业应用相关的先进微胶囊技术的见解（
signalword
Danger
hcodes
pcodes
Hazard Classifications
Acute Tox. 3 Oral
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
G Papaccio et al.
Journal of cellular biochemistry, 71(4), 479-490 (1998-11-25)
This study showed that citiolone (CIT), a free radical scavenger, significantly increased superoxide dismutase (P < 0.001 vs. untreated NOD, NMMA-treated, and silica-treated animals), catalase (P < 0.01 vs. untreated NOD), and glutathione peroxidase (P < 0.001 vs. untreated NOD
N Emonet et al.
Journal of photochemistry and photobiology. B, Biology, 40(1), 84-90 (1997-08-01)
The sensitivity of human dermal fibroblasts to UVA radiation has been linked to a decrease in intracellular glutathione (GSH) levels. GSH (gamma-glutamyl-cysteinyl-glycine) is a radical scavenger and a cofactor for protective enzymes such as selenium-dependent GSH peroxidases. In this study
G Papaccio
Diabetes research and clinical practice, 13(1-2), 95-102 (1991-08-01)
We used acetyl-homocysteine-thiolactone (citiolone) as an enhancer of superoxide dismutase (SOD), a free radical scavenger, in order to assay any possible prevention of the insulitis and subsequent B cell damage caused by streptozotocin (STZ) when given in multiple low doses.
C Bapu et al.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 17(1), 75-80 (1998-03-07)
The aim of our investigation was to examine the efficacy of monothiols and vitamins in the restoration of ion-dependent ATPases in mice intoxicated with methylmercury chloride (MMC). A daily dose of glutathione (GSH), N-acetyl-DL-homocysteine thiolactone (NAHT), vitamin B complex, or
Feng Qian
Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 29(4), 254-257 (2011-10-07)
To conjugate Plasmodium falciparum Pfs25 to recombinant Pseudomonas aeruginosa Exo-Protein A (rEPA) and test the effect of conjugation using different chemical linkers. The Pfs25 was thiolated by NAHT (DL-N-acetylhomocysteine thiolactone), whereas the carrier protein rEPA was modified by Sulfo-EMCS, EMCH
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