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经验公式(希尔记法):
C9H11N · HCl
化学文摘社编号:
分子量:
169.65
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
219-048-0
Beilstein/REAXYS Number:
3913700
MDL number:
Assay:
98%
Form:
crystals
InChI key
XEHNLVMHWYPNEQ-UHFFFAOYSA-N
InChI
1S/C9H11N.ClH/c10-9-5-7-3-1-2-4-8(7)6-9;/h1-4,9H,5-6,10H2;1H
SMILES string
Cl[H].NC1Cc2ccccc2C1
assay
98%
form
crystals
Quality Level
Application
产品由 2-茚醇经叠氮取代和后续的氢化作用制备。
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Tetrahedron, 61, 6801-6801 (2005)
J G Cannon et al.
Journal of medicinal chemistry, 29(10), 2016-2020 (1986-10-01)
The ortho hydroxy/methyl, hydroxy/hydroxymethyl, hydroxy/formyl, and hydroxy/carboxy substitution patterns, some of which confer dopaminergic agonist effects upon 2-aminotetralin ring systems, have been incorporated into beta-phenethylamine, 2-aminoindan, and trans-octahydrobenzo[f]quinoline rings. Certain of the 2-aminoindan derivatives displayed pharmacologic properties consistent with their
S X Ma et al.
The Journal of pharmacology and experimental therapeutics, 256(2), 751-756 (1991-02-01)
Dopaminergic structure-activity relationships of 2-aminoindans were evaluated for their ability to inhibit responses to stimulation of cardioaccelerator nerves in cats. The major observations were as follows: 1) Unsubstituted di-n-propyl- and diethyl 2-aminoindan derivatives do not inhibit responses to stimulation of
W Dimpfel et al.
BMC pharmacology, 11, 2-2 (2011-02-23)
Rasagiline, a new drug developed to treat Parkinson's disease, is known to inhibit monoamine oxidase B. However, its metabolite R-(-)-aminoindan does not show this kind of activity. The present series of in vitro experiments using the rat hippocampal slice preparation
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