ALD00376
Shi-Yu MPAA Ligand
别名:
N-[[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy]carbonyl]-L-leucine
表单
solid
反应适用性
reaction type: C-H Activation
reagent type: catalyst
reagent type: ligand
reaction type: Peptide Synthesis
官能团
amine
carboxylic acid
储存温度
2-8°C
SMILES字符串
O=C(O)[C@@H](NC(O[C@H]1[C@H](C(C)C)CC[C@@H](C)C1)=O)CC(C)C
InChI
1S/C17H31NO4/c1-10(2)8-14(16(19)20)18-17(21)22-15-9-12(5)6-7-13(15)11(3)4/h10-15H,6-9H2,1-5H3,(H,18,21)(H,19,20)/t12-,13+,14+,15-/m1/s1
InChI key
JDNKQMWGCKCHBF-CBBWQLFWSA-N
应用
Shi-Yu MPAA Ligand is a monoprotected α-amino acid that can be used as an effective chiral ligand in the asymmetric palladium-catalyzed alkylation reactions. It is also utilized in the alkylation of diphenyl(2-pyridyl)methane and isopropyl pyridines with alkyl boronic acids via enantioselective activation of C(sp2)-H and C(sp3)-H bonds, respectively.
The Shi-Yu MPAA Ligand has been reported by Yu and coworkers to promote the enantioselective C-H activation of cyclopropanes. This transformation is carried out through the coupling of organoboron reagents using palladium-mediated catalysis.
The Shi-Yu MPAA Ligand has been reported by Yu and coworkers to promote the enantioselective C-H activation of cyclopropanes. This transformation is carried out through the coupling of organoboron reagents using palladium-mediated catalysis.
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持