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Merck
CN

C1761

分支酸 来源于产气肠杆菌

≥80%

别名:

反式-3-([1-羧基乙烯基]氧)-4-羟基-1,5-环己二烯-1-羧酸

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关于此项目

经验公式(希尔记法):
C10H10O6
化学文摘社编号:
分子量:
226.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
≥80%
Form:
powder
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InChI

1S/C10H10O6/c1-5(9(12)13)16-8-4-6(10(14)15)2-3-7(8)11/h2-4,7-8,11H,1H2,(H,12,13)(H,14,15)/t7-,8-/m1/s1

SMILES string

O[C@@H]1C=CC(=C[C@H]1OC(=C)C(O)=O)C(O)=O

InChI key

WTFXTQVDAKGDEY-HTQZYQBOSA-N

assay

≥80%

form

powder

shipped in

dry ice

storage temp.

−20°C

Quality Level

Application

分支酸是一种代谢物,通常用于研究分支酸-预苯酯重排和合成分支酸衍生物。
通过莽草酸途径生物合成芳香氨基酸的中间体。

pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The mechanism of rearrangement of chorismic acid and related compounds.
Gajewski, Joseph J et al.
Journal of the American Chemical Society, 109(4), 1170-1186 (1987)
Gamma Chi et al.
Biochemistry, 51(24), 4868-4879 (2012-05-23)
MbtI is the salicylate synthase that catalyzes the first committed step in the synthesis of the iron chelating compound mycobactin in Mycobacterium tuberculosis. We previously developed a series of aromatic inhibitors against MbtI based on the reaction intermediate for this
Expanding the genetic code.
Wang, Lei and Schultz, Peter G
Angewandte Chemie (International Edition in English), 44(1), 34-66 (2005)
Alexandra Choutko et al.
Protein science : a publication of the Protein Society, 21(11), 1672-1681 (2012-08-18)
The protein chorismate mutase MtCM from Mycobacterium tuberculosis catalyzes one of the few pericyclic reactions known in biology: the transformation of chorismate to prephenate. Chorismate mutases have been widely studied experimentally and computationally to elucidate the transition state of the
Nivedita Nagachar et al.
FEMS microbiology letters, 308(2), 159-165 (2010-05-22)
Mycobacterium smegmatis acquires extracellular iron using exochelin, mycobactin and carboxymycobactin. The latter two siderophores are synthesized from salicylic acid, which, in turn, is derived from chorismic acid in the shikimic acid pathway. To understand the conversion mechanism of chorismic acid

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