G6104
甘氨酰胺 盐酸盐
98%
别名:
2-Aminoacetamide hydrochloride, Aminoacetamide hydrochloride, Glycine amide hydrochloride
质量水平
方案
98%
mp
204 °C (dec.) (lit.)
SMILES字符串
Cl.NCC(N)=O
InChI
1S/C2H6N2O.ClH/c3-1-2(4)5;/h1,3H2,(H2,4,5);1H
InChI key
WKNMKGVLOWGGOU-UHFFFAOYSA-N
应用
在生理 pH 值范围内可用的缓冲剂。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Gottfried K Schroeder et al.
Biochemistry, 46(13), 4037-4044 (2007-03-14)
As a model for mechanistic comparison with peptidyl transfer within the ribosome, the reaction of aqueous glycinamide with N-formylphenylalanine trifluoroethyl ester (fPhe-TFE) represents an improvement over earlier model reactions involving Tris. The acidity of trifluoroethanol (pKa 12.4) resembles that of
Brett C Bookser et al.
Journal of medicinal chemistry, 48(24), 7808-7820 (2005-11-24)
4-(Phenylamino)-5-phenyl-7-(5-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine 1 and related compounds known as "diaryltubercidin" analogues are potent inhibitors of adenosine kinase (AK) and are orally active in animal models of pain such as the rat formalin paw model (GP3269 ED50= 6.4 mg/kg). However, the utility of
Xiaodong Jia et al.
The Journal of organic chemistry, 78(18), 9450-9456 (2013-08-21)
A catalytic α-sp(3) C-H oxidation of peptides and glycine amides was achieved under radical cation salt catalysis in the presence of O2, producing a series of substituted quinolines. The scope of this reaction shows good functional group tolerance and high
Eric Loeser et al.
Analytical chemistry, 79(14), 5382-5391 (2007-05-29)
When mobile-phase salt content is increased, cationic analytes often show increased retention. This effect is generally attributed to chaotropic or ion pairing effects. However, a cation exclusion mechanism could explain the same effects. In this study, experimental conditions were manipulated
Hong Zhao et al.
Bioconjugate chemistry, 17(2), 341-351 (2006-03-16)
The utility of PEGylation for improving therapeutic protein pharmacology would be substantially expanded if the authentic protein drugs could be regenerated in vivo. Diminution of kinetic constants of both enzymes and protein ligands are commonly encountered following permanent bioconjugation with
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