H58005
4-喹啉醇
98%
别名:
4-羟基喹啉
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关于此项目
经验公式（希尔记法）:
C9H7NO
化学文摘社编号:
分子量:
145.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-268-2
Beilstein/REAXYS Number:
2900
MDL number:
Assay:
98%
InChI key
PMZDQRJGMBOQBF-UHFFFAOYSA-N
InChI
1S/C9H7NO/c11-9-5-6-10-8-4-2-1-3-7(8)9/h1-6H,(H,10,11)
SMILES string
Oc1ccnc2ccccc12
assay
98%
mp
200-202 °C (lit.)
Quality Level
General description
4-喹啉醇（4-喹诺酮）是形成抗菌剂如诺氟沙星、萘啶酸、环丙沙星和西沙星核心部分的一种喹诺酮化合物。
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Josip Podobnik et al.
Biomolecules, 10(11) (2020-11-19)
Juvenile delinquency is related to several biological factors, yet very few vulnerability biomarkers have been identified. Previous data suggest that the enzyme monoamine oxidase B (MAO-B) influences several personality traits linked to the propensity to engage in delinquent behavior. Building
Óscar M Bautista-Aguilera et al.
International journal of molecular sciences, 21(11) (2020-06-04)
In this communication, we report the synthesis and cholinesterase (ChE)/monoamine oxidase (MAO) inhibition of 19 quinolinones (QN1-19) and 13 dihydroquinolinones (DQN1-13) designed as potential multitarget small molecules (MSM) for Alzheimer's disease therapy. Contrary to our expectations, none of them showed
Charinya Khamphukdee et al.
Molecules (Basel, Switzerland), 23(9) (2018-09-12)
The previously unreported flavone glycoside, demethyltorosaflavone B (2) and the E-propenoic acid substituted flavone, torosaflavone E (3a), were isolated together with nine previously reported metabolites, including indole-3-carbaldehyde, oleanonic acid, vanillic acid, p-hydroxybenzoic acid, altheranthin (1a), alternanthin B (1b), demethyltorosaflavone D
Takeshi Fuchigami et al.
Nuclear medicine and biology, 35(2), 203-212 (2008-03-04)
High-affinity iodine- and ethyl-C-5 substituted analogs of 4-hydroxy-3-(3-[11C]methoxyphenyl)-2(1H)-quinolone ([11C]4HQ) were synthesized as new positron emission tomography radioligands for the glycine-binding sites of the N-methyl-d-aspartate (NMDA) ion channel. Although both radioligands showed high in vitro specific binding to rat brain slices
Roman Kimmel et al.
Carbohydrate research, 345(6), 768-779 (2010-03-09)
A comparative study for selective glucosylation of N-unsubstituted 4-hydroxyquinolin-2(1H)-ones into 4-(tetra-O-acetyl-beta-D-glucopyranosyloxy)quinolin-2(1H)-ones is reported. Four glycosyl donors including tetra-O-acetyl-alpha-D-glucopyranosyl bromide, beta-D-glucose pentaacetate, glucose tetraacetate and tetra-O-acetyl-alpha-D-glucopyranosyl trichloroacetimidate were tested, along with different promoters and reaction conditions. The best results were obtained
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