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线性分子式:
CH3OCOCH2CH2COOH
化学文摘社编号:
分子量:
132.11
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
223-408-2
Beilstein/REAXYS Number:
1722669
MDL number:
Assay:
95%
Form:
powder
InChI key
JDRMYOQETPMYQX-UHFFFAOYSA-N
InChI
1S/C5H8O4/c1-9-5(8)3-2-4(6)7/h2-3H2,1H3,(H,6,7)
SMILES string
COC(=O)CCC(O)=O
assay
95%
form
powder
bp
151 °C/20 mmHg (lit.)
mp
54-57 °C (lit.)
Quality Level
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
D L Eizirik et al.
Molecular and cellular endocrinology, 118(1-2), 71-83 (1996-04-19)
Nitric oxide (NO) has been proposed as a possible mediator of beta-cell damage in human IDDM. This hypothesis is based on in vitro studies with rodent pancreatic islets. In the present study we examined whether human beta-cells are affected by
Isabelle Briaud et al.
Diabetes, 51(3), 662-668 (2002-03-02)
Chronic elevations in plasma levels of fatty acids (FAs) adversely affect pancreatic beta-cell function in type 2 diabetes. In vitro, we have previously shown that deleterious effects of prolonged exposure of isolated islets to FAs were dependent on the presence
P Maechler et al.
The Journal of biological chemistry, 274(39), 27905-27913 (1999-09-17)
The effects of a transient exposure to hydrogen peroxide (10 min at 200 microM H(2)O(2)) on pancreatic beta cell signal transduction and insulin secretion have been evaluated. In rat islets, insulin secretion evoked by glucose (16.7 mM) or by the
Zrinka Rajić et al.
Molecules (Basel, Switzerland), 23(7) (2018-07-18)
Novel primaquine (PQ) and halogenaniline asymmetric fumardiamides 4a⁻f, potential Michael acceptors, and their reduced analogues succindiamides 5a⁻f were prepared by simple three-step reactions: coupling reaction between PQ and mono-ethyl fumarate (1a) or mono-methyl succinate (1b), hydrolysis of PQ-dicarboxylic acid mono-ester
A D Lajoix et al.
Diabetes, 50(6), 1311-1323 (2001-05-26)
Evidence is presented showing that a neuronal isoform of nitric oxide synthase (NOS) is expressed in rat pancreatic islets and INS-1 cells. Sequencing of the coding region indicated a 99.8% homology with rat neuronal NOS (nNOS) with four mutations, three
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