N162
R-(-)-尼古地平 盐酸盐
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关于此项目
经验公式（希尔记法）:
C36H39N3O6 · HCl
化学文摘社编号:
分子量:
646.17
UNSPSC Code:
12352005
PubChem Substance ID:
MDL number:
InChI
1S/C36H39N3O6.ClH/c1-25-31(34(40)44-3)33(27-12-10-17-30(24-27)39(42)43)32(26(2)37-25)35(41)45-23-11-20-38-21-18-36(19-22-38,28-13-6-4-7-14-28)29-15-8-5-9-16-29;/h4-10,12-17,24,33,37H,11,18-23H2,1-3H3;1H/t33-;/m1./s1
SMILES string
Cl.COC(=O)C1=C(C)NC(C)=C([C@@H]1c2cccc(c2)[N+]([O-])=O)C(=O)OCCCN3CCC(CC3)(c4ccccc4)c5ccccc5
InChI key
MHOSUIMBPQVOEU-MGDILKBHSA-N
optical activity
[α]23/D −12.5°, c = 0.14 in methanol(lit.)
color
pale yellow
solubility
methanol: soluble
storage temp.
−20°C
Biochem/physiol Actions
活性较低的对映体
Disclaimer
感光性。塑料对其有强吸附性。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
V Höllt et al.
Biochemical pharmacology, 43(12), 2601-2608 (1992-06-23)
The (-)-isomer of verapamil is 10-fold more potent as a calcium antagonist than the (+)-isomer. However, both enantiomers are equally effective in increasing cellular accumulation of anticancer drugs [Gruber et al., Int J Cancer 41: 224-226, 1988]. In addition to
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