InChI
1S/C20H41O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-19-22-20-18-21/h2-20H2,1H3
SMILES string
CCCCCCCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
InChI key
PSEGVHKUPXNGGJ-UHFFFAOYSA-N
form
solid
mp
44-46 °C (lit.)
HLB
15
Quality Level
General description
Brij® S20是一种表面活性剂，属于聚氧乙烯醚类。它主要用于药物应用中，以提高药物的溶解度。也可以将其嫁接在各种表面上，以增强染料的细胞内摄取。
Application
- 用于水飞蓟素口服给药的纳米结构脂质载体：提高水飞蓟素在2型糖尿病和代谢综合征模型中的吸收和体内疗效。：该研究利用Brij® S20开发出用于水飞蓟素口服给药的纳米结构脂质载体。研究结果表明，水飞蓟素在治疗2型糖尿病和代谢综合征方面的吸收率和疗效均有所提高，凸显了Brij® S20在改进给药系统方面的潜力。（Piazzini et al., 2019）。
- 通过电纺丝将水性分散体制成纳米纤维中的水稳定全生物降解微颗粒，用于生物技术植物保护。：该研究利用Brij® S20通过电纺丝在纳米纤维中制造出水稳定、可生物降解的微颗粒。这些微颗粒设计用于生物技术植物保护，证明了Brij® S20在农业生物技术方面的潜力（Bansal et al., 2012）。
Legal Information
Brij is a registered trademark of Croda International PLC
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Nanostructured lipid carriers as promising delivery systems for plant extracts: The case of silymarin
Piazzini V, et al.
Applied Sciences, 8(7), 1163-1163 (2018)
Brij-grafted-chitosan copolymers with function of P-glycoprotein modulation: Synthesis, characterization and in vitro investigations
Xiong W, et al.
Carbohydrate Polymers, 204, 89-96 (2019)
Wei Xiong et al.
International journal of nanomedicine, 13, 3781-3793 (2018-07-11)
Berberine (BBR) is a plant-derived benzylisoquinoline alkaloid and has been demonstrated to be a potential treatment for various chronic diseases. The poor water solubility and P-glycoprotein (Pgp)-mediated drug efflux are the main challenges for its further application in a clinical
Y C Lee et al.
Journal of pharmaceutical sciences, 86(4), 430-433 (1997-04-01)
An ocular insert is developed for the controlled systemic delivery of insulin. Commercially available Gelfoam absorbable gelatin sponge, USP, is used in the fabrication of the ocular insert in the form of a matrix system. Two eyedrop formulations and 13
J P Lens et al.
Journal of biomaterials science. Polymer edition, 8(12), 963-982 (1997-01-01)
Alkyl-poly(ethylene oxide) (PEO) surfactants containing a terminal hydroxyl, sulfate, or carboxylate group were grafted at the surface of poly(ethylene) (PE) samples to improve their blood compatibility. Grafting was achieved by immobilizing PEO surfactants on PE using an argon plasma treatment.
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